YBR249C

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Systematic name YBR249C
Gene name ARO4
Aliases
Feature type ORF, Verified
Coordinates Chr II:717994..716882
Primary SGDID S000000453


Description of YBR249C: 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP) synthase, catalyzes the first step in aromatic amino acid biosynthesis and is feedback-inhibited by tyrosine or high concentrations of phenylalanine or tryptophan[1][2][3]




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References

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  1. Helmstaedt K, et al. (2005) Evolution of 3-deoxy-D-arabino-heptulosonate-7-phosphate synthase-encoding genes in the yeast Saccharomyces cerevisiae. Proc Natl Acad Sci U S A 102(28):9784-9 SGD PMID 15987779
  2. Jones EW and Fink GR (1982) Regulation of amino acid and nucleotide biosynthesis in yeast. Pp.181-299 in The Molecular Biology of the Yeast Saccharomyces: Metabolism and Gene Expression, edited by Strathern JN, Jones EW and Broach JR. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory Press SGD PMID
  3. Kunzler M, et al. (1992) Cloning, primary structure and regulation of the ARO4 gene, encoding the tyrosine-inhibited 3-deoxy-D-arabino-heptulosonate-7-phosphate synthase from Saccharomyces cerevisiae. Gene 113(1):67-74 SGD PMID 1348717

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