YBR237W

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Systematic name YBR237W
Gene name PRP5
Aliases RNA5
Feature type ORF, Verified
Coordinates Chr II:691969..694518
Primary SGDID S000000441


Description of YBR237W: RNA helicase in the DEAD-box family, necessary for prespliceosome formation, bridges U1 and U2 snRNPs and enables stable U2 snRNP association with intron RNA[1][2][3]




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References

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  1. Abu Dayyeh BK, et al. (2002) Probing interactions between the U2 small nuclear ribonucleoprotein and the DEAD-box protein, Prp5. J Biol Chem 277(23):20221-33 SGD PMID 11927574
  2. Xu YZ, et al. (2004) Prp5 bridges U1 and U2 snRNPs and enables stable U2 snRNP association with intron RNA. EMBO J 23(2):376-85 SGD PMID 14713954
  3. de la Cruz J, et al. (1999) Unwinding RNA in Saccharomyces cerevisiae: DEAD-box proteins and related families. Trends Biochem Sci 24(5):192-8 SGD PMID 10322435

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