Difference between revisions of "YBR218C"
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| − | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl? | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?dbid=S000000422 YBR218C] |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''PYC2 '' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''PYC2 '' | ||
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | ||
|nowrap| Chr II:662244..658702 | |nowrap| Chr II:662244..658702 | ||
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| + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID''' || S000000422 | ||
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<br> | <br> | ||
| − | '''Description of | + | '''Description of YBR218C:''' Pyruvate carboxylase isoform, cytoplasmic enzyme that converts pyruvate to oxaloacetate; highly similar to isoform Pyc1p but differentially regulated; mutations in the human homolog are associated with lactic acidosis<ref name='S000058196'>Foury F (1997) Human genetic diseases: a cross-talk between man and yeast. Gene 195(1):1-10 {{SGDpaper|S000058196}} PMID 9300813</ref><ref name='S000051649'>Brewster NK, et al. (1994) Regulation of pyruvate carboxylase isozyme (PYC1, PYC2) gene expression in Saccharomyces cerevisiae during fermentative and nonfermentative growth. Arch Biochem Biophys 311(1):62-71 {{SGDpaper|S000051649}} PMID 8185321</ref><ref name='S000040003'>Walker ME, et al. (1991) Yeast pyruvate carboxylase: identification of two genes encoding isoenzymes. Biochem Biophys Res Commun 176(3):1210-7 |
{{SGDpaper|S000040003}} PMID 2039506</ref> | {{SGDpaper|S000040003}} PMID 2039506</ref> | ||
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J Biol Chem 278(5):3265-74</ref> | J Biol Chem 278(5):3265-74</ref> | ||
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Revision as of 08:45, 27 February 2007
Share your knowledge...Edit this entry! <protect>
| Systematic name | YBR218C |
| Gene name | PYC2 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr II:662244..658702 |
| Primary SGDID | S000000422 |
Description of YBR218C: Pyruvate carboxylase isoform, cytoplasmic enzyme that converts pyruvate to oxaloacetate; highly similar to isoform Pyc1p but differentially regulated; mutations in the human homolog are associated with lactic acidosis[1][2][3]
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Contents
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References
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- ↑ Foury F (1997) Human genetic diseases: a cross-talk between man and yeast. Gene 195(1):1-10 SGD PMID 9300813
- ↑ Brewster NK, et al. (1994) Regulation of pyruvate carboxylase isozyme (PYC1, PYC2) gene expression in Saccharomyces cerevisiae during fermentative and nonfermentative growth. Arch Biochem Biophys 311(1):62-71 SGD PMID 8185321
- ↑ Walker ME, et al. (1991) Yeast pyruvate carboxylase: identification of two genes encoding isoenzymes. Biochem Biophys Res Commun 176(3):1210-7 SGD PMID 2039506
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