Difference between revisions of "YBR217W"

From SGD-Wiki
Jump to: navigation, search
(Automated import of articles)
 
(Automated import of articles)
 
(9 intermediate revisions by the same user not shown)
Line 1: Line 1:
 
<!-- PLEASE DO NOT EDIT HERE. USE THE SECTION EDIT LINKS ON THE RIGHT MARGIN-->
 
<!-- PLEASE DO NOT EDIT HERE. USE THE SECTION EDIT LINKS ON THE RIGHT MARGIN-->
 
{{PageTop}}
 
{{PageTop}}
 +
<protect>
 
{|{{Prettytable}} align = 'right' width = '200px'
 
{|{{Prettytable}} align = 'right' width = '200px'
 
|-
 
|-
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?locus=YBR217W YBR217W]  
+
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000000421 YBR217W]  
 
|-
 
|-
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''ATG12 ''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''ATG12 ''
Line 12: Line 13:
 
|-
 
|-
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
|nowrap| Chr II:657827..658387
+
|nowrap| Chr II:657832..658392
 
|-
 
|-
|colspan = '3'|{{Don'tEditThisBox}}
+
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID'''          || S000000421
 
|}
 
|}
 
<br>
 
<br>
'''Description of {{PAGENAME}}:''' Ubiquitin-like modifier, conjugated via an isopeptide bond to a lysine residue of Atg5p by the E1 enzyme, Atg7p, and the E2 enzyme, Atg10p, a step that is essential for autophagy<ref name='S000051835'>Tsukada M and Ohsumi Y (1993) Isolation and characterization of autophagy-defective mutants of Saccharomyces cerevisiae. FEBS Lett 333(1-2):169-74 {{SGDpaper|S000051835}} PMID 8224160</ref><ref name='S000048125'>Tanida I, et al. (1999) Apg7p/Cvt2p: A novel protein-activating enzyme essential for autophagy. Mol Biol Cell 10(5):1367-79 {{SGDpaper|S000048125}} PMID 10233150</ref><ref name='S000045627'>Shintani T, et al. (1999) Apg10p, a novel protein-conjugating enzyme essential for autophagy in yeast. EMBO J 18(19):5234-41 {{SGDpaper|S000045627}} PMID 10508157</ref><ref name='S000039962'>Mizushima N, et al. (1998) A protein conjugation system essential for autophagy. Nature 395(6700):395-8
+
'''Description of YBR217W:''' Conserved ubiquitin-like modifier involved in autophagy and the Cvt pathway; conjugated to Atg5p to form a complex involved in Atg8p lipidation; Atg12p-Atg5p also forms a complex with Atg16p that is required for autophagosome formation<ref name='S000124888'>Hanada T, et al. (2007) The Atg12-Atg5 Conjugate Has a Novel E3-like Activity for Protein Lipidation in Autophagy. J Biol Chem 282(52):37298-302 {{SGDpaper|S000124888}} PMID 17986448</ref><ref name='S000069879'>Kuma A, et al. (2002) Formation of the approximately 350-kDa Apg12-Apg5.Apg16 multimeric complex, mediated by Apg16 oligomerization, is essential for autophagy in yeast. J Biol Chem 277(21):18619-25 {{SGDpaper|S000069879}} PMID 11897782</ref><ref name='S000039962'>Mizushima N, et al. (1998) A protein conjugation system essential for autophagy. Nature 395(6700):395-8 {{SGDpaper|S000039962}} PMID 9759731</ref><ref name='S000045627'>Shintani T, et al. (1999) Apg10p, a novel protein-conjugating enzyme essential for autophagy in yeast. EMBO J 18(19):5234-41 {{SGDpaper|S000045627}} PMID 10508157</ref><ref name='S000048125'>Tanida I, et al. (1999) Apg7p/Cvt2p: A novel protein-activating enzyme essential for autophagy. Mol Biol Cell 10(5):1367-79 {{SGDpaper|S000048125}} PMID 10233150</ref><ref name='S000051835'>Tsukada M and Ohsumi Y (1993) Isolation and characterization of autophagy-defective mutants of Saccharomyces cerevisiae. FEBS Lett 333(1-2):169-74
  {{SGDpaper|S000039962}} PMID 9759731</ref>
+
  {{SGDpaper|S000051835}} PMID 8224160</ref>
 
<br>
 
<br>
 
<br>
 
<br>
 
<br>
 
<br>
 
<br>
 
<br>
 
+
<br>
 +
</protect>
 
__TOC__
 
__TOC__
 
==Community Commentary==
 
==Community Commentary==
 
{{CommentaryHelp}}
 
{{CommentaryHelp}}
  
 +
 +
 +
 +
<!-- PLEASE ADD Community Commentary ABOVE THIS MESSAGE. See below for an example of community annotation -->
 +
<!--
 +
Specifically higher expression in carbon limited chemostat cultures versus carbon excess.
 +
<ref>Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur.
 +
J Biol Chem 278(5):3265-74</ref>
 +
-->
 +
 +
 +
 +
<protect>
 
==References==
 
==References==
 
<!-- REFERENCES ARE AUTOMATICALLY GENERATED.  PLEASE DON'T EDIT THIS SECTION-->
 
<!-- REFERENCES ARE AUTOMATICALLY GENERATED.  PLEASE DON'T EDIT THIS SECTION-->
 
{{RefHelp}}
 
{{RefHelp}}
 +
</protect>

Latest revision as of 07:45, 23 January 2012

Share your knowledge...Edit this entry! <protect>

Systematic name YBR217W
Gene name ATG12
Aliases APG12
Feature type ORF, Verified
Coordinates Chr II:657832..658392
Primary SGDID S000000421


Description of YBR217W: Conserved ubiquitin-like modifier involved in autophagy and the Cvt pathway; conjugated to Atg5p to form a complex involved in Atg8p lipidation; Atg12p-Atg5p also forms a complex with Atg16p that is required for autophagosome formation[1][2][3][4][5][6]




</protect>

Community Commentary

About Community Commentary. Please share your knowledge!




<protect>

References

See Help:References on how to add references

  1. Hanada T, et al. (2007) The Atg12-Atg5 Conjugate Has a Novel E3-like Activity for Protein Lipidation in Autophagy. J Biol Chem 282(52):37298-302 SGD PMID 17986448
  2. Kuma A, et al. (2002) Formation of the approximately 350-kDa Apg12-Apg5.Apg16 multimeric complex, mediated by Apg16 oligomerization, is essential for autophagy in yeast. J Biol Chem 277(21):18619-25 SGD PMID 11897782
  3. Mizushima N, et al. (1998) A protein conjugation system essential for autophagy. Nature 395(6700):395-8 SGD PMID 9759731
  4. Shintani T, et al. (1999) Apg10p, a novel protein-conjugating enzyme essential for autophagy in yeast. EMBO J 18(19):5234-41 SGD PMID 10508157
  5. Tanida I, et al. (1999) Apg7p/Cvt2p: A novel protein-activating enzyme essential for autophagy. Mol Biol Cell 10(5):1367-79 SGD PMID 10233150
  6. Tsukada M and Ohsumi Y (1993) Isolation and characterization of autophagy-defective mutants of Saccharomyces cerevisiae. FEBS Lett 333(1-2):169-74 SGD PMID 8224160

See Help:Categories on how to add the wiki page for this gene to a Category </protect>