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Systematic name YBR204C
Gene name LDH1
Feature type ORF, Verified
Coordinates Chr II:633381..632254
Primary SGDID S000000408

Description of YBR204C: Serine hydrolase; exhibits active esterase plus weak triacylglycerol lipase activities; proposed role in lipid homeostasis, regulating phospholipid and non-polar lipid levels and required for mobilization of LD-stored lipids; localizes to the lipid droplet (LD) surface; contains a classical serine containing catalytic triad (GxSxG motif)[1][2][3]


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  1. Baxter SM, et al. (2004) Synergistic computational and experimental proteomics approaches for more accurate detection of active serine hydrolases in yeast. Mol Cell Proteomics 3(3):209-25 SGD PMID 14645503
  2. Debelyy MO, et al. (2011) Involvement of the yeast hydrolase Ldh1p in lipid homeostasis. Eukaryot Cell () SGD PMID 21478434
  3. Giaever G, et al. (2002) Functional profiling of the Saccharomyces cerevisiae genome. Nature 418(6896):387-91 SGD PMID 12140549

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