Difference between revisions of "YBR179C"

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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
|nowrap| Chr II:589109..586542
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|nowrap| Chr II:589114..586547
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID'''          || S000000383
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID'''          || S000000383

Revision as of 14:05, 3 February 2011

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Systematic name YBR179C
Gene name FZO1
Aliases
Feature type ORF, Verified
Coordinates Chr II:589114..586547
Primary SGDID S000000383


Description of YBR179C: Mitofusin, mitochondrial integral membrane protein involved in mitochondrial fusion and mitochondrial genome maintenance; contains N-terminal GTPase domain; targeted for destruction by cytosolic components of the ubiquitin-proteasome system[1][2][3]




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References

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  1. Cohen MM, et al. (2008) Ubiquitin-Proteasome-dependent Degradation of a Mitofusin, a Critical Regulator of Mitochondrial Fusion. Mol Biol Cell 19(6):2457-64 SGD PMID 18353967
  2. Hermann GJ, et al. (1998) Mitochondrial fusion in yeast requires the transmembrane GTPase Fzo1p. J Cell Biol 143(2):359-73 SGD PMID 9786948
  3. Rapaport D, et al. (1998) Fzo1p is a mitochondrial outer membrane protein essential for the biogenesis of functional mitochondria in Saccharomyces cerevisiae. J Biol Chem 273(32):20150-5 SGD PMID 9685359

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