YBR173C

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Systematic name YBR173C
Gene name UMP1
Aliases
Feature type ORF, Verified
Coordinates Chr II:582167..581721
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Description of YBR173C: Short-lived chaperone required for correct maturation of the 20S proteasome; degraded by proteasome upon completion of its assembly; involved in ubiquitin-mediated proteolysis; mutant defective in degradation of short-lived proteins[1][2][3]



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References

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  1. Bochtler M, et al. (1999) The proteasome. Annu Rev Biophys Biomol Struct 28():295-317 SGD PMID 10410804
  2. Maurizi MR (1998) Proteasome assembly: biting the hand. Curr Biol 8(13):R453-6 SGD PMID 9651672
  3. Ramos PC, et al. (1998) Ump1p is required for proper maturation of the 20S proteasome and becomes its substrate upon completion of the assembly. Cell 92(4):489-99 SGD PMID 9491890

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