YBR173C
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| Systematic name | YBR173C |
| Gene name | UMP1 |
| Aliases | RNS2 |
| Feature type | ORF, Verified |
| Coordinates | Chr II:582167..581721 |
| Primary SGDID | S000000377 |
Description of YBR173C: Short-lived chaperone required for correct maturation of the 20S proteasome; may inhibit premature dimerization of proteasome half-mers; degraded by proteasome upon completion of its assembly[1][2][3][4]
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References
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- ↑ Ramos PC, et al. (1998) Ump1p is required for proper maturation of the 20S proteasome and becomes its substrate upon completion of the assembly. Cell 92(4):489-99 SGD PMID 9491890
- ↑ Maurizi MR (1998) Proteasome assembly: biting the hand. Curr Biol 8(13):R453-6 SGD PMID 9651672
- ↑ Bochtler M, et al. (1999) The proteasome. Annu Rev Biophys Biomol Struct 28:295-317 SGD PMID 10410804
- ↑ Li X, et al. (2007) beta-Subunit appendages promote 20S proteasome assembly by overcoming an Ump1-dependent checkpoint. EMBO J 26(9):2339-49 SGD PMID 17431397
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