Difference between revisions of "YBR173C"

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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?locus=YBR173C YBR173C]  
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000000377 YBR173C]  
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''UMP1 ''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''UMP1 ''
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Aliases'''          ||'' ''
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Aliases'''          ||''RNS2''
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Feature type'''          || ORF, Verified[[Category:ORF]][[Category:ORF, Verified]]
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Feature type'''          || ORF, Verified[[Category:ORF]][[Category:ORF, Verified]]
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
|nowrap| Chr II:582167..581721
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|nowrap| Chr II:582172..581726
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID'''          || S000000377
 
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'''Description of {{PAGENAME}}:''' Short-lived chaperone required for correct maturation of the 20S proteasome; degraded by proteasome upon completion of its assembly; involved in ubiquitin-mediated proteolysis; mutant defective in degradation of short-lived proteins<ref name='S000064679'>Bochtler M, et al. (1999) The proteasome. Annu Rev Biophys Biomol Struct 28():295-317 {{SGDpaper|S000064679}} PMID 10410804</ref><ref name='S000063601'>Maurizi MR (1998) Proteasome assembly: biting the hand. Curr Biol 8(13):R453-6 {{SGDpaper|S000063601}} PMID 9651672</ref><ref name='S000041323'>Ramos PC, et al. (1998) Ump1p is required for proper maturation of the 20S proteasome and becomes its substrate upon completion of the assembly. Cell 92(4):489-99
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'''Description of YBR173C:''' Short-lived chaperone required for correct maturation of the 20S proteasome; may inhibit premature dimerization of proteasome half-mers; degraded by proteasome upon completion of its assembly<ref name='S000064679'>Bochtler M, et al. (1999) The proteasome. Annu Rev Biophys Biomol Struct 28:295-317 {{SGDpaper|S000064679}} PMID 10410804</ref><ref name='S000122233'>Li X, et al. (2007) beta-Subunit appendages promote 20S proteasome assembly by overcoming an Ump1-dependent checkpoint. EMBO J 26(9):2339-49 {{SGDpaper|S000122233}} PMID 17431397</ref><ref name='S000063601'>Maurizi MR (1998) Proteasome assembly: biting the hand. Curr Biol 8(13):R453-6 {{SGDpaper|S000063601}} PMID 9651672</ref><ref name='S000041323'>Ramos PC, et al. (1998) Ump1p is required for proper maturation of the 20S proteasome and becomes its substrate upon completion of the assembly. Cell 92(4):489-99
 
  {{SGDpaper|S000041323}} PMID 9491890</ref>
 
  {{SGDpaper|S000041323}} PMID 9491890</ref>
 
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==Community Commentary==
 
==Community Commentary==
 
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Specifically higher expression in carbon limited chemostat cultures versus carbon excess.
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<ref>Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur.
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J Biol Chem 278(5):3265-74</ref>
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Specifically higher expression in carbon limited chemostat cultures versus carbon excess.
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<ref>Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur.
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J Biol Chem 278(5):3265-74</ref>
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==References==
 
==References==
 
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Latest revision as of 07:45, 23 January 2012

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Systematic name YBR173C
Gene name UMP1
Aliases RNS2
Feature type ORF, Verified
Coordinates Chr II:582172..581726
Primary SGDID S000000377


Description of YBR173C: Short-lived chaperone required for correct maturation of the 20S proteasome; may inhibit premature dimerization of proteasome half-mers; degraded by proteasome upon completion of its assembly[1][2][3][4]




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Community Commentary

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References

See Help:References on how to add references

  1. Bochtler M, et al. (1999) The proteasome. Annu Rev Biophys Biomol Struct 28:295-317 SGD PMID 10410804
  2. Li X, et al. (2007) beta-Subunit appendages promote 20S proteasome assembly by overcoming an Ump1-dependent checkpoint. EMBO J 26(9):2339-49 SGD PMID 17431397
  3. Maurizi MR (1998) Proteasome assembly: biting the hand. Curr Biol 8(13):R453-6 SGD PMID 9651672
  4. Ramos PC, et al. (1998) Ump1p is required for proper maturation of the 20S proteasome and becomes its substrate upon completion of the assembly. Cell 92(4):489-99 SGD PMID 9491890

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