Difference between revisions of "YBR170C"
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | ||
| − | |nowrap| Chr II: | + | |nowrap| Chr II:578086..576344 |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID''' || S000000374 | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID''' || S000000374 | ||
Revision as of 14:05, 3 February 2011
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| Systematic name | YBR170C |
| Gene name | NPL4 |
| Aliases | HRD4 |
| Feature type | ORF, Verified |
| Coordinates | Chr II:578086..576344 |
| Primary SGDID | S000000374 |
Description of YBR170C: Endoplasmic reticulum and nuclear membrane protein, forms a complex with Cdc48p and Ufd1p that recognizes ubiquitinated proteins in the endoplasmic reticulum and delivers them to the proteasome for degradation[1][2][3]
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Contents
Community Commentary
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References
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- ↑ Bays NW and Hampton RY (2002) Cdc48-Ufd1-Npl4: stuck in the middle with Ub. Curr Biol 12(10):R366-71 SGD PMID 12015140
- ↑ Bays NW, et al. (2001) HRD4/NPL4 is required for the proteasomal processing of ubiquitinated ER proteins. Mol Biol Cell 12(12):4114-28 SGD PMID 11739805
- ↑ Hitchcock AL, et al. (2001) The conserved npl4 protein complex mediates proteasome-dependent membrane-bound transcription factor activation. Mol Biol Cell 12(10):3226-41 SGD PMID 11598205
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