Difference between revisions of "YBR170C"
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| − | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl? | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?dbid=S000000374 YBR170C] |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''NPL4 '' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''NPL4 '' | ||
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | ||
|nowrap| Chr II:578081..576339 | |nowrap| Chr II:578081..576339 | ||
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| + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID''' || S000000374 | ||
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<br> | <br> | ||
| − | '''Description of | + | '''Description of YBR170C:''' Endoplasmic reticulum and nuclear membrane protein, forms a complex with Cdc48p and Ufd1p that recognizes ubiquitinated proteins in the endoplasmic reticulum and delivers them to the proteasome for degradation<ref name='S000071485'>Bays NW and Hampton RY (2002) Cdc48-Ufd1-Npl4: stuck in the middle with Ub. Curr Biol 12(10):R366-71 {{SGDpaper|S000071485}} PMID 12015140</ref><ref name='S000069870'>Bays NW, et al. (2001) HRD4/NPL4 is required for the proteasomal processing of ubiquitinated ER proteins. Mol Biol Cell 12(12):4114-28 {{SGDpaper|S000069870}} PMID 11739805</ref><ref name='S000066133'>Hitchcock AL, et al. (2001) The conserved npl4 protein complex mediates proteasome-dependent membrane-bound transcription factor activation. Mol Biol Cell 12(10):3226-41 |
{{SGDpaper|S000066133}} PMID 11598205</ref> | {{SGDpaper|S000066133}} PMID 11598205</ref> | ||
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J Biol Chem 278(5):3265-74</ref> | J Biol Chem 278(5):3265-74</ref> | ||
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Revision as of 08:45, 27 February 2007
Share your knowledge...Edit this entry! <protect>
| Systematic name | YBR170C |
| Gene name | NPL4 |
| Aliases | HRD4 |
| Feature type | ORF, Verified |
| Coordinates | Chr II:578081..576339 |
| Primary SGDID | S000000374 |
Description of YBR170C: Endoplasmic reticulum and nuclear membrane protein, forms a complex with Cdc48p and Ufd1p that recognizes ubiquitinated proteins in the endoplasmic reticulum and delivers them to the proteasome for degradation[1][2][3]
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Contents
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References
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- ↑ Bays NW and Hampton RY (2002) Cdc48-Ufd1-Npl4: stuck in the middle with Ub. Curr Biol 12(10):R366-71 SGD PMID 12015140
- ↑ Bays NW, et al. (2001) HRD4/NPL4 is required for the proteasomal processing of ubiquitinated ER proteins. Mol Biol Cell 12(12):4114-28 SGD PMID 11739805
- ↑ Hitchcock AL, et al. (2001) The conserved npl4 protein complex mediates proteasome-dependent membrane-bound transcription factor activation. Mol Biol Cell 12(10):3226-41 SGD PMID 11598205
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