Difference between revisions of "YBR170C"
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| − | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http:// | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000000374 YBR170C] |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''NPL4 '' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''NPL4 '' | ||
Revision as of 07:45, 23 January 2012
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| Systematic name | YBR170C |
| Gene name | NPL4 |
| Aliases | HRD4 |
| Feature type | ORF, Verified |
| Coordinates | Chr II:578086..576344 |
| Primary SGDID | S000000374 |
Description of YBR170C: Ubiquitin-binding protein involved in protein degradation; Cdc48p-Npl4p-Ufd1p complex participates in ER-associated degradation (ERAD) while Cdc48p-Npl4p-Vms1p complex participates in mitochondria-associated degradation (MAD)[1][2][3][4]
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Contents
Community Commentary
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References
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- ↑ Bays NW and Hampton RY (2002) Cdc48-Ufd1-Npl4: stuck in the middle with Ub. Curr Biol 12(10):R366-71 SGD PMID 12015140
- ↑ Bays NW, et al. (2001) HRD4/NPL4 is required for the proteasomal processing of ubiquitinated ER proteins. Mol Biol Cell 12(12):4114-28 SGD PMID 11739805
- ↑ Heo JM, et al. (2010) A stress-responsive system for mitochondrial protein degradation. Mol Cell 40(3):465-80 SGD PMID 21070972
- ↑ Hitchcock AL, et al. (2001) The conserved npl4 protein complex mediates proteasome-dependent membrane-bound transcription factor activation. Mol Biol Cell 12(10):3226-41 SGD PMID 11598205
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