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Systematic name YBR159W
Gene name IFA38
Feature type ORF, Verified
Coordinates Chr II:558685..559728
Primary SGDID S000000363

Description of YBR159W: Microsomal beta-keto-reductase; contains oleate response element (ORE) sequence in the promoter region; mutants exhibit reduced VLCFA synthesis, accumulate high levels of dihydrosphingosine, phytosphingosine and medium-chain ceramides[1][2]


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  1. Beaudoin F, et al. (2002) A Saccharomyces cerevisiae gene required for heterologous fatty acid elongase activity encodes a microsomal beta-keto-reductase. J Biol Chem 277(13):11481-8 SGD PMID 11792704
  2. Han G, et al. (2002) The Saccharomyces cerevisiae YBR159w gene encodes the 3-ketoreductase of the microsomal fatty acid elongase. J Biol Chem 277(38):35440-9 SGD PMID 12087109

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