Difference between revisions of "YBR159W"

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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?locus=YBR159W YBR159W]  
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?dbid=S000000363 YBR159W]  
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''IFA38 ''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''IFA38 ''
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
 
|nowrap| Chr II:558679..559722
 
|nowrap| Chr II:558679..559722
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID'''          || S000000363
 
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'''Description of {{PAGENAME}}:''' Microsomal beta-keto-reductase; contains oleate response element (ORE) sequence in the promoter region; mutants exhibit reduced VLCFA synthesis, accumulate high levels of dihydrosphingosine, phytosphingosine and medium-chain ceramides<ref name='S000115906'>Weaver C, et al. (2006)  Acta Univ Palacki Olomuc Fac Med () {{SGDpaper|S000115906}} PMID </ref><ref name='S000071362'>Han G, et al. (2002) The Saccharomyces cerevisiae YBR159w gene encodes the 3-ketoreductase of the microsomal fatty acid elongase. J Biol Chem 277(38):35440-9 {{SGDpaper|S000071362}} PMID 12087109</ref><ref name='S000069482'>Beaudoin F, et al. (2002) A Saccharomyces cerevisiae gene required for heterologous fatty acid elongase activity encodes a microsomal beta-keto-reductase. J Biol Chem 277(13):11481-8
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'''Description of YBR159W:''' Microsomal beta-keto-reductase; contains oleate response element (ORE) sequence in the promoter region; mutants exhibit reduced VLCFA synthesis, accumulate high levels of dihydrosphingosine, phytosphingosine and medium-chain ceramides<ref name='S000115906'>Weaver C, et al. (2006)  Acta Univ Palacki Olomuc Fac Med () {{SGDpaper|S000115906}} PMID </ref><ref name='S000071362'>Han G, et al. (2002) The Saccharomyces cerevisiae YBR159w gene encodes the 3-ketoreductase of the microsomal fatty acid elongase. J Biol Chem 277(38):35440-9 {{SGDpaper|S000071362}} PMID 12087109</ref><ref name='S000069482'>Beaudoin F, et al. (2002) A Saccharomyces cerevisiae gene required for heterologous fatty acid elongase activity encodes a microsomal beta-keto-reductase. J Biol Chem 277(13):11481-8
 
  {{SGDpaper|S000069482}} PMID 11792704</ref>
 
  {{SGDpaper|S000069482}} PMID 11792704</ref>
 
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J Biol Chem 278(5):3265-74</ref>
 
J Biol Chem 278(5):3265-74</ref>
 
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Revision as of 08:45, 27 February 2007

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Systematic name YBR159W
Gene name IFA38
Aliases
Feature type ORF, Verified
Coordinates Chr II:558679..559722
Primary SGDID S000000363


Description of YBR159W: Microsomal beta-keto-reductase; contains oleate response element (ORE) sequence in the promoter region; mutants exhibit reduced VLCFA synthesis, accumulate high levels of dihydrosphingosine, phytosphingosine and medium-chain ceramides[1][2][3]




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References

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  1. Weaver C, et al. (2006) Acta Univ Palacki Olomuc Fac Med () SGD PMID
  2. Han G, et al. (2002) The Saccharomyces cerevisiae YBR159w gene encodes the 3-ketoreductase of the microsomal fatty acid elongase. J Biol Chem 277(38):35440-9 SGD PMID 12087109
  3. Beaudoin F, et al. (2002) A Saccharomyces cerevisiae gene required for heterologous fatty acid elongase activity encodes a microsomal beta-keto-reductase. J Biol Chem 277(13):11481-8 SGD PMID 11792704

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