Difference between revisions of "YBR140C"
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| + | Specifically higher expression in carbon limited chemostat cultures versus carbon excess. | ||
| + | <ref>Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur. | ||
| + | J Biol Chem 278(5):3265-74</ref> | ||
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Revision as of 13:02, 21 February 2007
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| Systematic name | YBR140C |
| Gene name | IRA1 |
| Aliases | GLC1, PPD1 |
| Feature type | ORF, Verified |
| Coordinates | Chr II:526622..517344 |
Description of YBR140C: GTPase-activating protein that negatively regulates RAS by converting it from the GTP- to the GDP-bound inactive form, required for reducing cAMP levels under nutrient limiting conditions, mediates membrane association of adenylate cyclase[1][2]
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References
See Help:References on how to add references
- ↑ Tanaka K, et al. (1989) IRA1, an inhibitory regulator of the RAS-cyclic AMP pathway in Saccharomyces cerevisiae. Mol Cell Biol 9(2):757-68 SGD PMID 2540426
- ↑ Mitts MR, et al. (1991) Interactions between adenylate cyclase and the yeast GTPase-activating protein IRA1. Mol Cell Biol 11(9):4591-8 SGD PMID 1875942
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