YBR138C

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Systematic name YBR138C
Gene name
Aliases HDR1
Feature type ORF, Uncharacterized
Coordinates Chr II:515336..513762
Primary SGDID S000000342


Description of YBR138C: Cytoplasmic protein of unknown function, potentially phosphorylated by Cdc28p; YBR138C is not an essential gene[1][2][3]




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Protein Details

Protein Modification

Modification(s): Phosphorylation

Identified as an efficient substrate of Clb2-Cdk1-as1 in a screen of a proteomic GST-fusion library. [3] [4]


This gene is part of the UW-Stout Orphan Gene Project. Learn more here.

Growth Curve

YBR138C YPD.png

In a BY4735 background, knocking out YBR138C seems to have no effect on growth rate in log-phase. In this assay, the BY4735 strain's doubling time was 414 minutes, while the YBR138C knock-out strain's doubling time was 432minutes. (These doubling times are the means of three experiments.)

Caffeine and Yeast Cells

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References

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  1. Huh WK, et al. (2003) Global analysis of protein localization in budding yeast. Nature 425(6959):686-91 SGD PMID 14562095
  2. Kucharczyk R, et al. (1999) Disruption of six novel yeast genes located on chromosome II reveals one gene essential for vegetative growth and two required for sporulation and conferring hypersensitivity to various chemicals. Yeast 15(10B):987-1000 SGD PMID 10407278
  3. 3.0 3.1 Ubersax JA, et al. (2003) Targets of the cyclin-dependent kinase Cdk1. Nature 425(6960):859-64 SGD PMID 14574415 Cite error: Invalid <ref> tag; name "S000074306" defined multiple times with different content
  4. submitted by Jeff Ubersax on 2004-01-21

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