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Systematic name YBR130C
Gene name SHE3
Feature type ORF, Verified
Coordinates Chr II:496869..495592
Primary SGDID S000000334

Description of YBR130C: Protein that acts as an adaptor between Myo4p and the She2p-mRNA complex; part of the mRNA localization machinery that restricts accumulation of certain proteins to the bud; also required for cortical ER inheritance[1][2][3][4][5]


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  1. Bohl F, et al. (2000) She2p, a novel RNA-binding protein tethers ASH1 mRNA to the Myo4p myosin motor via She3p. EMBO J 19(20):5514-24 SGD PMID 11032818
  2. Estrada P, et al. (2003) Myo4p and She3p are required for cortical ER inheritance in Saccharomyces cerevisiae. J Cell Biol 163(6):1255-66 SGD PMID 14691136
  3. Long RM, et al. (2000) She2p is a novel RNA-binding protein that recruits the Myo4p-She3p complex to ASH1 mRNA. EMBO J 19(23):6592-601 SGD PMID 11101531
  4. Shepard KA, et al. (2003) Widespread cytoplasmic mRNA transport in yeast: identification of 22 bud-localized transcripts using DNA microarray analysis. Proc Natl Acad Sci U S A 100(20):11429-34 SGD PMID 13679573
  5. Takizawa PA and Vale RD (2000) The myosin motor, Myo4p, binds Ash1 mRNA via the adapter protein, She3p. Proc Natl Acad Sci U S A 97(10):5273-8 SGD PMID 10792032

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