YBR125C

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Systematic name YBR125C
Gene name PTC4
Aliases GCT1
Feature type ORF, Verified
Coordinates Chr II:488374..487193
Primary SGDID S000000329


Description of YBR125C: Cytoplasmic type 2C protein phosphatase (PP2C); identified as a high-copy number suppressor of cnb1 mpk1 synthetic lethality; overexpression decreases high-osmolarity induced Hog1p phosphorylation and kinase activity[1][2][3]




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References

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  1. Cheng A, et al. (1999) Dephosphorylation of cyclin-dependent kinases by type 2C protein phosphatases. Genes Dev 13(22):2946-57 SGD PMID 10580002
  2. Huh WK, et al. (2003) Global analysis of protein localization in budding yeast. Nature 425(6959):686-91 SGD PMID 14562095
  3. Shitamukai A, et al. (2004) Evidence for antagonistic regulation of cell growth by the calcineurin and high osmolarity glycerol pathways in Saccharomyces cerevisiae. J Biol Chem 279(5):3651-61 SGD PMID 14583627

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