Difference between revisions of "YBR112C"
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| − | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http:// | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000000316 YBR112C] |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''CYC8 '' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''CYC8 '' | ||
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| − | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Aliases''' ||''CRT8, SSN6'' | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Aliases''' ||''CRT8, SSN6, [OCT1+], [OCT]'' |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Feature type''' || ORF, Verified[[Category:ORF]][[Category:ORF, Verified]] | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Feature type''' || ORF, Verified[[Category:ORF]][[Category:ORF, Verified]] | ||
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | ||
| − | |nowrap| Chr II: | + | |nowrap| Chr II:465770..462870 |
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| − | | | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID''' || S000000316 |
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| − | '''Description of | + | '''Description of YBR112C:''' General transcriptional co-repressor, acts together with Tup1p; also acts as part of a transcriptional co-activator complex that recruits the SWI/SNF and SAGA complexes to promoters; can form the prion [OCT+]<ref name='S000129327'>Patel BK, et al. (2009) The yeast global transcriptional co-repressor protein Cyc8 can propagate as a prion. Nat Cell Biol 11(3):344-9 {{SGDpaper|S000129327}} PMID 19219034</ref><ref name='S000070269'>Proft M and Struhl K (2002) Hog1 kinase converts the Sko1-Cyc8-Tup1 repressor complex into an activator that recruits SAGA and SWI/SNF in response to osmotic stress. Mol Cell 9(6):1307-17 {{SGDpaper|S000070269}} PMID 12086627</ref><ref name='S000043101'>Smith RL and Johnson AD (2000) Turning genes off by Ssn6-Tup1: a conserved system of transcriptional repression in eukaryotes. Trends Biochem Sci 25(7):325-30 |
{{SGDpaper|S000043101}} PMID 10871883</ref> | {{SGDpaper|S000043101}} PMID 10871883</ref> | ||
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==Community Commentary== | ==Community Commentary== | ||
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| + | <!-- PLEASE ADD Community Commentary ABOVE THIS MESSAGE. See below for an example of community annotation --> | ||
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| + | Specifically higher expression in carbon limited chemostat cultures versus carbon excess. | ||
| + | <ref>Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur. | ||
| + | J Biol Chem 278(5):3265-74</ref> | ||
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==References== | ==References== | ||
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Latest revision as of 07:45, 23 January 2012
Share your knowledge...Edit this entry! <protect>
| Systematic name | YBR112C |
| Gene name | CYC8 |
| Aliases | CRT8, SSN6, [OCT1+], [OCT] |
| Feature type | ORF, Verified |
| Coordinates | Chr II:465770..462870 |
| Primary SGDID | S000000316 |
Description of YBR112C: General transcriptional co-repressor, acts together with Tup1p; also acts as part of a transcriptional co-activator complex that recruits the SWI/SNF and SAGA complexes to promoters; can form the prion [OCT+][1][2][3]
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Contents
Community Commentary
About Community Commentary. Please share your knowledge!
Interactions
Other Interactions
Other Topic: functional dependence
Other Interactions interaction with Nrg1
Repression by LexA-Nrg1 of a heterologous promoter containing lexA binding sites depends on Cyc8/Ssn6. [4] [5]
Physical
Physical interaction with Nrg1
Nrg1 interacts with Ssn6/Cyc8 in the two-hybrid system, and in GST pull-down experiments. [4] [5]
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References
See Help:References on how to add references
- ↑ Patel BK, et al. (2009) The yeast global transcriptional co-repressor protein Cyc8 can propagate as a prion. Nat Cell Biol 11(3):344-9 SGD PMID 19219034
- ↑ Proft M and Struhl K (2002) Hog1 kinase converts the Sko1-Cyc8-Tup1 repressor complex into an activator that recruits SAGA and SWI/SNF in response to osmotic stress. Mol Cell 9(6):1307-17 SGD PMID 12086627
- ↑ Smith RL and Johnson AD (2000) Turning genes off by Ssn6-Tup1: a conserved system of transcriptional repression in eukaryotes. Trends Biochem Sci 25(7):325-30 SGD PMID 10871883
- ↑ 4.0 4.1 Park SH, et al. (1999) Nrg1 is a transcriptional repressor for glucose repression of STA1 gene expression in Saccharomyces cerevisiae. Mol Cell Biol 19(3):2044-50 SGD PMID 10022891
- ↑ 5.0 5.1 submitted by Valmik K. Vyas on 2003-02-12
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