From SGD-Wiki
Jump to: navigation, search

Share your knowledge...Edit this entry! <protect>

Systematic name YBR107C
Gene name IML3
Aliases MCM19
Feature type ORF, Verified
Coordinates Chr II:454530..453793
Primary SGDID S000000311

Description of YBR107C: Outer kinetochore protein and component of the Ctf19 complex; involved in the establishment of pericentromeric cohesion during mitosis; prevents non-disjunction of sister chromatids during meiosis II; required for localization of Sgo1p to pericentric sites during meiosis I; orthologous to human centromere constitutive-associated network (CCAN) subunit CENP-L and fission yeast fta1[1][2][3][4][5]


Community Commentary

About Community Commentary. Please share your knowledge!



See Help:References on how to add references

  1. Fernius J and Marston AL (2009) Establishment of cohesion at the pericentromere by the Ctf19 kinetochore subcomplex and the replication fork-associated factor, Csm3. PLoS Genet 5(9):e1000629 SGD PMID 19730685
  2. Ghosh SK, et al. (2001) The IML3/MCM19 gene of Saccharomyces cerevisiae is required for a kinetochore-related process during chromosome segregation. Mol Genet Genomics 265(2):249-57 SGD PMID 11361335
  3. Ghosh SK, et al. (2004) The Iml3 protein of the budding yeast is required for the prevention of precocious sister chromatid separation in meiosis I and for sister chromatid disjunction in meiosis II. Curr Genet 46(2):82-91 SGD PMID 15241623
  4. Pot I, et al. (2003) Chl4p and iml3p are two new members of the budding yeast outer kinetochore. Mol Biol Cell 14(2):460-76 SGD PMID 12589047
  5. Schleiffer A, et al. (2012) CENP-T proteins are conserved centromere receptors of the Ndc80 complex. Nat Cell Biol 14(6):604-13 SGD PMID 22561346

See Help:Categories on how to add the wiki page for this gene to a Category </protect>