Difference between revisions of "YBR103W"

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Specifically higher expression in carbon limited chemostat cultures versus carbon excess.
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<ref>Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur.
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J Biol Chem 278(5):3265-74</ref>
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Revision as of 12:02, 21 February 2007

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Systematic name YBR103W
Gene name SIF2
Aliases EMB1
Feature type ORF, Verified
Coordinates Chr II:447703..449310


Description of YBR103W: WD40 repeat-containing subunit of the Set3C histone deacetylase complex, which represses early/middle sporulation genes; antagonizes telomeric silencing; binds specifically to the Sir4p N-terminus[1][2][3]




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References

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  1. Gasser SM, et al. (1998) Nuclear organization and silencing: trafficking of Sir proteins. Novartis Found Symp 214():114-26; discussion 126-32 SGD PMID 9601014
  2. Pijnappel WW, et al. (2001) The S. cerevisiae SET3 complex includes two histone deacetylases, Hos2 and Hst1, and is a meiotic-specific repressor of the sporulation gene program. Genes Dev 15(22):2991-3004 SGD PMID 11711434
  3. Cockell M, et al. (1998) Sif2p interacts with Sir4p amino-terminal domain and antagonizes telomeric silencing in yeast. Curr Biol 8(13):787-90 SGD PMID 9651685

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