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Systematic name YBR098W
Gene name MMS4
Aliases SLX2, YBR100W
Feature type ORF, Verified
Coordinates Chr II:441509..443584
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Description of YBR098W: Subunit of the structure-specific Mms4p-Mus81p endonuclease that cleaves branched DNA; involved in recombination and DNA repair[1][2][3]

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  1. Bastin-Shanower SA, et al. (2003) The mechanism of Mus81-Mms4 cleavage site selection distinguishes it from the homologous endonuclease Rad1-Rad10. Mol Cell Biol 23(10):3487-96 SGD PMID 12724407
  2. Kaliraman V, et al. (2001) Functional overlap between Sgs1-Top3 and the Mms4-Mus81 endonuclease. Genes Dev 15(20):2730-40 SGD PMID 11641278
  3. Xiao W, et al. (1998) Mms4, a putative transcriptional (co)activator, protects Saccharomyces cerevisiae cells from endogenous and environmental DNA damage. Mol Gen Genet 257(6):614-23 SGD PMID 9604884

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