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Systematic name YBR091C
Gene name TIM12
Aliases MRS5
Feature type ORF, Verified
Coordinates Chr II:427484..427155
Primary SGDID S000000295

Description of YBR091C: Essential protein of the inner mitochondrial membrane, peripherally localized; component of the TIM22 complex, which is a twin-pore translocase that mediates insertion of numerous multispanning inner membrane proteins[1][2]


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  1. Jarosch E, et al. (1996) Mrs5p, an essential protein of the mitochondrial intermembrane space, affects protein import into yeast mitochondria. J Biol Chem 271(29):17219-25 SGD PMID 8663351
  2. Rehling P, et al. (2003) Protein insertion into the mitochondrial inner membrane by a twin-pore translocase. Science 299(5613):1747-51 SGD PMID 12637749

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