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Systematic name YBR080C
Gene name SEC18
Aliases ANU4
Feature type ORF, Verified
Coordinates Chr II:400884..398608
Primary SGDID S000000284

Description of YBR080C: ATPase required for vesicular transport between ER and Golgi, the 'priming' step in homotypic vacuole fusion, autophagy, and protein secretion; releases Sec17p from SNAP complexes; has similarity to mammalian NSF[1][2][3][4]


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  1. Mayer A, et al. (1996) Sec18p (NSF)-driven release of Sec17p (alpha-SNAP) can precede docking and fusion of yeast vacuoles. Cell 85(1):83-94 SGD PMID 8620540
  2. Newman AP and Ferro-Novick S (1990) Defining components required for transport from the ER to the Golgi complex in yeast. Bioessays 12(10):485-91 SGD PMID 2082939
  3. Ungermann C, et al. (1998) A vacuolar v-t-SNARE complex, the predominant form in vivo and on isolated vacuoles, is disassembled and activated for docking and fusion. J Cell Biol 140(1):61-9 SGD PMID 9425154
  4. Wilson DW, et al. (1989) A fusion protein required for vesicle-mediated transport in both mammalian cells and yeast. Nature 339(6223):355-9 SGD PMID 2657434

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