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Systematic name YBR080C
Gene name SEC18
Aliases ANU4
Feature type ORF, Verified
Coordinates Chr II:400884..398608
Primary SGDID S000000284

Description of YBR080C: ATPase required for the release of Sec17p during the 'priming' step in homotypic vacuole fusion and for ER to Golgi transport; homolog of the mammalian NSF[1][2][3]


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  1. Kato M and Wickner W (2003) Vam10p defines a Sec18p-independent step of priming that allows yeast vacuole tethering. Proc Natl Acad Sci U S A 100(11):6398-403 SGD PMID 12748377
  2. Mayer A, et al. (1996) Sec18p (NSF)-driven release of Sec17p (alpha-SNAP) can precede docking and fusion of yeast vacuoles. Cell 85(1):83-94 SGD PMID 8620540
  3. Newman AP and Ferro-Novick S (1990) Defining components required for transport from the ER to the Golgi complex in yeast. Bioessays 12(10):485-91 SGD PMID 2082939

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