Difference between revisions of "YBR079C"

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'''Description of YBR079C:''' eIF3a subunit of the core complex of translation initiation factor 3 (eIF3), essential for translation; part of a subcomplex (Prt1p-Rpg1p-Nip1p) that stimulates binding of mRNA and tRNA(i)Met to ribosomes<ref name='S000043795'>Phan L, et al. (1998) Identification of a translation initiation factor 3 (eIF3) core complex, conserved in yeast and mammals, that interacts with eIF5. Mol Cell Biol 18(8):4935-46 {{SGDpaper|S000043795}} PMID 9671501</ref><ref name='S000060771'>Phan L, et al. (2001) A subcomplex of three eIF3 subunits binds eIF1 and eIF5 and stimulates ribosome binding of mRNA and tRNA(i)Met. EMBO J 20(11):2954-65 {{SGDpaper|S000060771}} PMID 11387228</ref><ref name='S000073119'>Valasek L, et al. (2003) The yeast eIF3 subunits TIF32/a, NIP1/c, and eIF5 make critical connections with the 40S ribosome in vivo. Genes Dev 17(6):786-99
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'''Description of YBR079C:''' eIF3a subunit of the core complex of translation initiation factor 3 (eIF3), essential for translation; part of a Prt1p-Rpg1p-Nip1p subcomplex that stimulates binding of mRNA and tRNA(i)Met to ribosomes; involved in translation reinitiation<ref name='S000135410'>Cuchalova L, et al. (2010) The RNA Recognition Motif of Eukaryotic Translation Initiation Factor 3g (eIF3g) Is Required for Resumption of Scanning of Posttermination Ribosomes for Reinitiation on GCN4 and Together with eIF3i Stimulates Linear Scanning. Mol Cell Biol 30(19):4671-86 {{SGDpaper|S000135410}} PMID 20679478</ref><ref name='S000043795'>Phan L, et al. (1998) Identification of a translation initiation factor 3 (eIF3) core complex, conserved in yeast and mammals, that interacts with eIF5. Mol Cell Biol 18(8):4935-46 {{SGDpaper|S000043795}} PMID 9671501</ref><ref name='S000060771'>Phan L, et al. (2001) A subcomplex of three eIF3 subunits binds eIF1 and eIF5 and stimulates ribosome binding of mRNA and tRNA(i)Met. EMBO J 20(11):2954-65 {{SGDpaper|S000060771}} PMID 11387228</ref><ref name='S000073119'>Valasek L, et al. (2003) The yeast eIF3 subunits TIF32/a, NIP1/c, and eIF5 make critical connections with the 40S ribosome in vivo. Genes Dev 17(6):786-99
 
  {{SGDpaper|S000073119}} PMID 12651896</ref>
 
  {{SGDpaper|S000073119}} PMID 12651896</ref>
 
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Revision as of 14:05, 14 January 2011

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Systematic name YBR079C
Gene name RPG1
Aliases TIF32
Feature type ORF, Verified
Coordinates Chr II:398271..395377
Primary SGDID S000000283


Description of YBR079C: eIF3a subunit of the core complex of translation initiation factor 3 (eIF3), essential for translation; part of a Prt1p-Rpg1p-Nip1p subcomplex that stimulates binding of mRNA and tRNA(i)Met to ribosomes; involved in translation reinitiation[1][2][3][4]




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References

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  1. Cuchalova L, et al. (2010) The RNA Recognition Motif of Eukaryotic Translation Initiation Factor 3g (eIF3g) Is Required for Resumption of Scanning of Posttermination Ribosomes for Reinitiation on GCN4 and Together with eIF3i Stimulates Linear Scanning. Mol Cell Biol 30(19):4671-86 SGD PMID 20679478
  2. Phan L, et al. (1998) Identification of a translation initiation factor 3 (eIF3) core complex, conserved in yeast and mammals, that interacts with eIF5. Mol Cell Biol 18(8):4935-46 SGD PMID 9671501
  3. Phan L, et al. (2001) A subcomplex of three eIF3 subunits binds eIF1 and eIF5 and stimulates ribosome binding of mRNA and tRNA(i)Met. EMBO J 20(11):2954-65 SGD PMID 11387228
  4. Valasek L, et al. (2003) The yeast eIF3 subunits TIF32/a, NIP1/c, and eIF5 make critical connections with the 40S ribosome in vivo. Genes Dev 17(6):786-99 SGD PMID 12651896

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