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Systematic name YBR073W
Gene name RDH54
Aliases TID1
Feature type ORF, Verified
Coordinates Chr II:383112..385988
Primary SGDID S000000277

Description of YBR073W: DNA-dependent ATPase; stimulates strand exchange by modifying the topology of double-stranded DNA; involved in recombinational repair of DNA double-strand breaks during mitosis and meiosis; proposed to be involved in crossover interference; interacts with Dmc1p; stimulates Dmc1p and Rad51p[1][2][3][4][5]


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  1. Dresser ME, et al. (1997) DMC1 functions in a Saccharomyces cerevisiae meiotic pathway that is largely independent of the RAD51 pathway. Genetics 147(2):533-44 SGD PMID 9335591
  2. Klein HL (1997) RDH54, a RAD54 homologue in Saccharomyces cerevisiae, is required for mitotic diploid-specific recombination and repair and for meiosis. Genetics 147(4):1533-43 SGD PMID 9409819
  3. Nimonkar AV, et al. (2012) Saccharomyces cerevisiae Dmc1 and Rad51 preferentially function with Tid1 and Rad54, respectively, to promote DNA strand invasion during genetic recombination. J Biol Chem () SGD PMID 22761450
  4. Petukhova G, et al. (2000) Promotion of Rad51-dependent D-loop formation by yeast recombination factor Rdh54/Tid1. Genes Dev 14(17):2206-15 SGD PMID 10970884
  5. Shinohara M, et al. (2003) Crossover interference in Saccharomyces cerevisiae requires a TID1/RDH54- and DMC1-dependent pathway. Genetics 163(4):1273-86 SGD PMID 12702674

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