Difference between revisions of "YBR069C"

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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?dbid=S000000273 YBR069C]  
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000000273 YBR069C]  
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''TAT1 ''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''TAT1 ''

Revision as of 06:45, 23 January 2012

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Systematic name YBR069C
Gene name TAT1
Aliases TAP1, VAP1
Feature type ORF, Verified
Coordinates Chr II:378433..376574
Primary SGDID S000000273


Description of YBR069C: Amino acid transport protein for valine, leucine, isoleucine, and tyrosine, low-affinity tryptophan and histidine transporter; overexpression confers FK506 and FTY720 resistance[1][2][3][4][5]




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References

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  1. Bajmoczi M, et al. (1998) TAT1 encodes a low-affinity histidine transporter in Saccharomyces cerevisiae. Biochem Biophys Res Commun 243(1):205-9 SGD PMID 9473505
  2. Heitman J, et al. (1993) The immunosuppressant FK506 inhibits amino acid import in Saccharomyces cerevisiae. Mol Cell Biol 13(8):5010-9 SGD PMID 7687745
  3. Regenberg B, et al. (1999) Substrate specificity and gene expression of the amino-acid permeases in Saccharomyces cerevisiae. Curr Genet 36(6):317-28 SGD PMID 10654085
  4. Schmidt A, et al. (1994) Two FK506 resistance-conferring genes in Saccharomyces cerevisiae, TAT1 and TAT2, encode amino acid permeases mediating tyrosine and tryptophan uptake. Mol Cell Biol 14(10):6597-606 SGD PMID 7523855
  5. Welsch CA, et al. (2003) Ubiquitin pathway proteins influence the mechanism of action of the novel immunosuppressive drug FTY720 in Saccharomyces cerevisiae. J Biol Chem 278(29):26976-82 SGD PMID 12709439

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