Difference between revisions of "YBR069C"

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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''TAT1 ''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''TAT1 ''
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Aliases'''          ||''VAP1''
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Aliases'''          ||''TAP1, VAP1''
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Feature type'''          || ORF, Verified[[Category:ORF]][[Category:ORF, Verified]]
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Feature type'''          || ORF, Verified[[Category:ORF]][[Category:ORF, Verified]]
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'''Description of YBR069C:''' Amino acid transport protein for valine, leucine, isoleucine, and tyrosine, low-affinity tryptophan and histidine transporter; overexpression confers FK506 resistance<ref name='S000053575'>Bajmoczi M, et al. (1998) TAT1 encodes a low-affinity histidine transporter in Saccharomyces cerevisiae. Biochem Biophys Res Commun 243(1):205-9 {{SGDpaper|S000053575}} PMID 9473505</ref><ref name='S000044967'>Schmidt A, et al. (1994) Two FK506 resistance-conferring genes in Saccharomyces cerevisiae, TAT1 and TAT2, encode amino acid permeases mediating tyrosine and tryptophan uptake. Mol Cell Biol 14(10):6597-606 {{SGDpaper|S000044967}} PMID 7523855</ref><ref name='S000043244'>Regenberg B, et al. (1999) Substrate specificity and gene expression of the amino-acid permeases in Saccharomyces cerevisiae. Curr Genet 36(6):317-28
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'''Description of YBR069C:''' Amino acid transport protein for valine, leucine, isoleucine, and tyrosine, low-affinity tryptophan and histidine transporter; overexpression confers FK506 and FTY720 resistance<ref name='S000073661'>Welsch CA, et al. (2003) Ubiquitin pathway proteins influence the mechanism of action of the novel immunosuppressive drug FTY720 in Saccharomyces cerevisiae. J Biol Chem 278(29):26976-82 {{SGDpaper|S000073661}} PMID 12709439</ref><ref name='S000053575'>Bajmoczi M, et al. (1998) TAT1 encodes a low-affinity histidine transporter in Saccharomyces cerevisiae. Biochem Biophys Res Commun 243(1):205-9 {{SGDpaper|S000053575}} PMID 9473505</ref><ref name='S000044967'>Schmidt A, et al. (1994) Two FK506 resistance-conferring genes in Saccharomyces cerevisiae, TAT1 and TAT2, encode amino acid permeases mediating tyrosine and tryptophan uptake. Mol Cell Biol 14(10):6597-606 {{SGDpaper|S000044967}} PMID 7523855</ref><ref name='S000043244'>Regenberg B, et al. (1999) Substrate specificity and gene expression of the amino-acid permeases in Saccharomyces cerevisiae. Curr Genet 36(6):317-28 {{SGDpaper|S000043244}} PMID 10654085</ref><ref name='S000041878'>Heitman J, et al. (1993) The immunosuppressant FK506 inhibits amino acid import in Saccharomyces cerevisiae. Mol Cell Biol 13(8):5010-9
  {{SGDpaper|S000043244}} PMID 10654085</ref>
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  {{SGDpaper|S000041878}} PMID 7687745</ref>
 
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Revision as of 14:05, 28 November 2007

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Systematic name YBR069C
Gene name TAT1
Aliases TAP1, VAP1
Feature type ORF, Verified
Coordinates Chr II:378430..376571
Primary SGDID S000000273


Description of YBR069C: Amino acid transport protein for valine, leucine, isoleucine, and tyrosine, low-affinity tryptophan and histidine transporter; overexpression confers FK506 and FTY720 resistance[1][2][3][4][5]




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References

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  1. Welsch CA, et al. (2003) Ubiquitin pathway proteins influence the mechanism of action of the novel immunosuppressive drug FTY720 in Saccharomyces cerevisiae. J Biol Chem 278(29):26976-82 SGD PMID 12709439
  2. Bajmoczi M, et al. (1998) TAT1 encodes a low-affinity histidine transporter in Saccharomyces cerevisiae. Biochem Biophys Res Commun 243(1):205-9 SGD PMID 9473505
  3. Schmidt A, et al. (1994) Two FK506 resistance-conferring genes in Saccharomyces cerevisiae, TAT1 and TAT2, encode amino acid permeases mediating tyrosine and tryptophan uptake. Mol Cell Biol 14(10):6597-606 SGD PMID 7523855
  4. Regenberg B, et al. (1999) Substrate specificity and gene expression of the amino-acid permeases in Saccharomyces cerevisiae. Curr Genet 36(6):317-28 SGD PMID 10654085
  5. Heitman J, et al. (1993) The immunosuppressant FK506 inhibits amino acid import in Saccharomyces cerevisiae. Mol Cell Biol 13(8):5010-9 SGD PMID 7687745

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