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Systematic name YBR065C
Gene name ECM2
Aliases SLT11
Feature type ORF, Verified
Coordinates Chr II:369676..368582
Primary SGDID S000000269

Description of YBR065C: Pre-mRNA splicing factor, facilitates the cooperative formation of U2/U6 helix II in association with stem II in the spliceosome, function may be regulated by Slu7p[1][2][3]


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  1. Ben-Yehuda S, et al. (2000) Genetic and physical interactions between factors involved in both cell cycle progression and pre-mRNA splicing in Saccharomyces cerevisiae. Genetics 156(4):1503-17 SGD PMID 11102353
  2. Xu D and Friesen JD (2001) Splicing factor slt11p and its involvement in formation of U2/U6 helix II in activation of the yeast spliceosome. Mol Cell Biol 21(4):1011-23 SGD PMID 11158289
  3. Xu D, et al. (1998) Synthetic lethality of yeast slt mutations with U2 small nuclear RNA mutations suggests functional interactions between U2 and U5 snRNPs that are important for both steps of pre-mRNA splicing. Mol Cell Biol 18(4):2055-66 SGD PMID 9528778

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