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Systematic name YBR061C
Gene name TRM7
Feature type ORF, Verified
Coordinates Chr II:365719..364787
Primary SGDID S000000265

Description of YBR061C: 2'-O-ribose methyltransferase; methylates the 2'-O-ribose of tRNA-Phe, tRNA-Trp, and tRNA-Leu at positions C32 and N34 of the tRNA anticodon loop; crucial biological role likely modification of tRNA-Phe; interacts with Trm732p and Rtt10p in 2'-O-methylation of C32 and N34 substrate tRNAs, respectively[1][2]


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  1. Guy MP, et al. (2012) Yeast Trm7 interacts with distinct proteins for critical modifications of the tRNAPhe anticodon loop. RNA () SGD PMID 22912484
  2. Pintard L, et al. (2002) Trm7p catalyses the formation of two 2'-O-methylriboses in yeast tRNA anticodon loop. EMBO J 21(7):1811-20 SGD PMID 11927565

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