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Systematic name YBR058C-A
Gene name TSC3
Feature type ORF, Verified
Coordinates Chr II:356566..356324
Primary SGDID S000007521

Description of YBR058C-A: Protein that stimulates the activity of serine palmitoyltransferase (Lcb1p, Lcb2p) several-fold; involved in sphingolipid biosynthesis[1][2]


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See Help:References on how to add references

  1. Gable K, et al. (2000) Tsc3p is an 80-amino acid protein associated with serine palmitoyltransferase and required for optimal enzyme activity. J Biol Chem 275(11):7597-603 SGD PMID 10713067
  2. Monaghan E, et al. (2002) Mutations in the Lcb2p subunit of serine palmitoyltransferase eliminate the requirement for the TSC3 gene in Saccharomyces cerevisiae. Yeast 19(8):659-70 SGD PMID 12185836

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