Difference between revisions of "YBR043C"
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| − | '''Description of YBR043C:''' Multidrug transporter of the major facilitator superfamily, required for resistance to quinidine, barban, cisplatin, and bleomycin<ref name='S000061823'>Rieger KJ, et al. (1999) Chemotyping of yeast mutants using robotics. Yeast 15(10B):973-86 {{SGDpaper|S000061823}} PMID 10407277</ref><ref name='S000080433'>Tenreiro S, et al. (2005) The yeast multidrug transporter Qdr3 (Ybr043c): localization and role as a determinant of resistance to quinidine, barban, cisplatin, and bleomycin. Biochem Biophys Res Commun 327(3):952-9 | + | '''Description of YBR043C:''' Multidrug transporter of the major facilitator superfamily, has a role in polyamine homeostasis; expression is upregulated under polyamine stress; required for resistance to quinidine, barban, cisplatin, and bleomycin<ref name='S000061823'>Rieger KJ, et al. (1999) Chemotyping of yeast mutants using robotics. Yeast 15(10B):973-86 {{SGDpaper|S000061823}} PMID 10407277</ref><ref name='S000142425'>Teixeira MC, et al. (2010) Yeast response and tolerance to polyamine toxicity involving the drug:H+ antiporter Qdr3 and the transcription factors Yap1 and Gcn4. Microbiology () {{SGDpaper|S000142425}} PMID 21148207</ref><ref name='S000080433'>Tenreiro S, et al. (2005) The yeast multidrug transporter Qdr3 (Ybr043c): localization and role as a determinant of resistance to quinidine, barban, cisplatin, and bleomycin. Biochem Biophys Res Commun 327(3):952-9 |
{{SGDpaper|S000080433}} PMID 15649438</ref> | {{SGDpaper|S000080433}} PMID 15649438</ref> | ||
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Revision as of 14:05, 17 February 2011
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| Systematic name | YBR043C |
| Gene name | QDR3 |
| Aliases | AQR2 |
| Feature type | ORF, Verified |
| Coordinates | Chr II:323945..321876 |
| Primary SGDID | S000000247 |
Description of YBR043C: Multidrug transporter of the major facilitator superfamily, has a role in polyamine homeostasis; expression is upregulated under polyamine stress; required for resistance to quinidine, barban, cisplatin, and bleomycin[1][2][3]
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References
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- ↑ Rieger KJ, et al. (1999) Chemotyping of yeast mutants using robotics. Yeast 15(10B):973-86 SGD PMID 10407277
- ↑ Teixeira MC, et al. (2010) Yeast response and tolerance to polyamine toxicity involving the drug:H+ antiporter Qdr3 and the transcription factors Yap1 and Gcn4. Microbiology () SGD PMID 21148207
- ↑ Tenreiro S, et al. (2005) The yeast multidrug transporter Qdr3 (Ybr043c): localization and role as a determinant of resistance to quinidine, barban, cisplatin, and bleomycin. Biochem Biophys Res Commun 327(3):952-9 SGD PMID 15649438
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