Difference between revisions of "YBR038W"

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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?dbid=S000000242 YBR038W]  
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000000242 YBR038W]  
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''CHS2 ''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''CHS2 ''
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
|nowrap| Chr II:311897..314788
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|nowrap| Chr II:311898..314789
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID'''          || S000000242
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID'''          || S000000242
 
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'''Description of YBR038W:''' Chitin synthase II, requires activation from zymogenic form in order to catalyze the transfer of N-acetylglucosamine (GlcNAc) to chitin; required for the synthesis of chitin in the primary septum during cytokinesis<ref name='S000050095'>Shaw JA, et al. (1991) The function of chitin synthases 2 and 3 in the Saccharomyces cerevisiae cell cycle. J Cell Biol 114(1):111-23 {{SGDpaper|S000050095}} PMID 2050738</ref><ref name='S000057374'>Cid VJ, et al. (1995) Molecular basis of cell integrity and morphogenesis in Saccharomyces cerevisiae. Microbiol Rev 59(3):345-86 {{SGDpaper|S000057374}} PMID 7565410</ref><ref name='S000069165'>Schmidt M, et al. (2002) In budding yeast, contraction of the actomyosin ring and formation of the primary septum at cytokinesis depend on each other. J Cell Sci 115(Pt 2):293-302
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'''Description of YBR038W:''' Chitin synthase II; catalyzes transfer of N-acetylglucosamine (GlcNAc) to chitin upon activation of zymogenic form; required for chitin synthesis in the primary septum during cytokinesis; localization regulated by Cdk1p during mitosis<ref name='S000057374'>Cid VJ, et al. (1995) Molecular basis of cell integrity and morphogenesis in Saccharomyces cerevisiae. Microbiol Rev 59(3):345-86 {{SGDpaper|S000057374}} PMID 7565410</ref><ref name='S000069165'>Schmidt M, et al. (2002) In budding yeast, contraction of the actomyosin ring and formation of the primary septum at cytokinesis depend on each other. J Cell Sci 115(Pt 2):293-302 {{SGDpaper|S000069165}} PMID 11839781</ref><ref name='S000050095'>Shaw JA, et al. (1991) The function of chitin synthases 2 and 3 in the Saccharomyces cerevisiae cell cycle. J Cell Biol 114(1):111-23 {{SGDpaper|S000050095}} PMID 2050738</ref><ref name='S000131348'>Teh EM, et al. (2009) Retention of Chs2p in the ER requires N-terminal CDK1-phosphorylation sites. Cell Cycle 8(18):2964-74
  {{SGDpaper|S000069165}} PMID 11839781</ref>
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  {{SGDpaper|S000131348}} PMID 19713768</ref>
 
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Latest revision as of 06:45, 23 January 2012

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Systematic name YBR038W
Gene name CHS2
Aliases
Feature type ORF, Verified
Coordinates Chr II:311898..314789
Primary SGDID S000000242


Description of YBR038W: Chitin synthase II; catalyzes transfer of N-acetylglucosamine (GlcNAc) to chitin upon activation of zymogenic form; required for chitin synthesis in the primary septum during cytokinesis; localization regulated by Cdk1p during mitosis[1][2][3][4]




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Protein Details

Protein Modification

Modification(s): Phosphorylation

Identified as an efficient substrate of Clb2-Cdk1-as1 in a screen of a proteomic GST-fusion library. [5] [6]





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References

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  1. Cid VJ, et al. (1995) Molecular basis of cell integrity and morphogenesis in Saccharomyces cerevisiae. Microbiol Rev 59(3):345-86 SGD PMID 7565410
  2. Schmidt M, et al. (2002) In budding yeast, contraction of the actomyosin ring and formation of the primary septum at cytokinesis depend on each other. J Cell Sci 115(Pt 2):293-302 SGD PMID 11839781
  3. Shaw JA, et al. (1991) The function of chitin synthases 2 and 3 in the Saccharomyces cerevisiae cell cycle. J Cell Biol 114(1):111-23 SGD PMID 2050738
  4. Teh EM, et al. (2009) Retention of Chs2p in the ER requires N-terminal CDK1-phosphorylation sites. Cell Cycle 8(18):2964-74 SGD PMID 19713768
  5. Ubersax JA, et al. (2003) Targets of the cyclin-dependent kinase Cdk1. Nature 425(6960):859-64 SGD PMID 14574415
  6. submitted by Jeff Ubersax on 2004-01-21

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