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Systematic name YBR034C
Gene name HMT1
Aliases HCP1, ODP1, RMT1
Feature type ORF, Verified
Coordinates Chr II:305976..304930

Description of YBR034C: Nuclear SAM-dependent mono- and asymmetric arginine dimethylating methyltransferase that modifies hnRNPs, including Npl3p and Hrp1p, thus facilitating nuclear export of these proteins; required for viability of npl3 mutants[1][2][3]


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  1. Gary JD, et al. (1996) The predominant protein-arginine methyltransferase from Saccharomyces cerevisiae. J Biol Chem 271(21):12585-94 SGD PMID 8647869
  2. Shen EC, et al. (1998) Arginine methylation facilitates the nuclear export of hnRNP proteins. Genes Dev 12(5):679-91 SGD PMID 9499403
  3. Henry MF and Silver PA (1996) A novel methyltransferase (Hmt1p) modifies poly(A)+-RNA-binding proteins. Mol Cell Biol 16(7):3668-78 SGD PMID 8668183

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