YBR025C

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Systematic name YBR025C
Gene name OLA1
Aliases
Feature type ORF, Verified
Coordinates Chr II:291865..290681
Primary SGDID S000000229


Description of YBR025C: P-loop ATPase with similarity to human OLA1 and bacterial YchF; identified as specifically interacting with the proteasome; protein abundance increases in response to hydrogen peroxide and to DNA replication stress[1][2][3][4]




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Protein Details

Protein Localization

Protein identified in a purified mitochondrial extract. [5] [6]





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References

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  1. Godon C, et al. (1998) The H2O2 stimulon in Saccharomyces cerevisiae. J Biol Chem 273(35):22480-9 SGD PMID 9712873
  2. Guerrero C, et al. (2006) An integrated mass spectrometry-based proteomic approach: quantitative analysis of tandem affinity-purified in vivo cross-linked protein complexes (QTAX) to decipher the 26 S proteasome-interacting network. Mol Cell Proteomics 5(2):366-78 SGD PMID 16284124
  3. Koller-Eichhorn R, et al. (2007) Human OLA1 Defines an ATPase Subfamily in the Obg Family of GTP-binding Proteins. J Biol Chem 282(27):19928-37 SGD PMID 17430889
  4. Tkach JM, et al. (2012) Dissecting DNA damage response pathways by analysing protein localization and abundance changes during DNA replication stress.LID - 10.1038/ncb2549 [doi] Nat Cell Biol () SGD PMID 22842922
  5. Ohlmeier S, et al. (2004) The yeast mitochondrial proteome, a study of fermentative and respiratory growth. J Biol Chem 279(6):3956-79 SGD PMID 14597615
  6. submitted by Steffen Ohlmeier on 2004-04-08

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