Difference between revisions of "YBL105C"
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| − | '''Description of YBL105C:''' Protein serine/threonine kinase essential for cell wall remodeling during growth; localized to sites of polarized growth and the mother-daughter bud neck; homolog of the alpha, beta, and gamma isoforms of mammalian protein kinase C (PKC)<ref name=' | + | '''Description of YBL105C:''' Protein serine/threonine kinase essential for cell wall remodeling during growth; localized to sites of polarized growth and the mother-daughter bud neck; homolog of the alpha, beta, and gamma isoforms of mammalian protein kinase C (PKC)<ref name='S000049517'>Watanabe M, et al. (1994) Saccharomyces cerevisiae PKC1 encodes a protein kinase C (PKC) homolog with a substrate specificity similar to that of mammalian PKC. J Biol Chem 269(24):16829-36 {{SGDpaper|S000049517}} PMID 8207005</ref><ref name='S000049103'>Andrews PD and Stark MJ (2000) Dynamic, Rho1p-dependent localization of Pkc1p to sites of polarized growth. J Cell Sci 113 ( Pt 15):2685-93 {{SGDpaper|S000049103}} PMID 10893184</ref><ref name='S000041609'>Levin DE, et al. (1994) Dissecting the protein kinase C/MAP kinase signalling pathway of Saccharomyces cerevisiae. Cell Mol Biol Res 40(3):229-39 |
| − | {{SGDpaper| | + | {{SGDpaper|S000041609}} PMID 7874200</ref> |
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Revision as of 14:05, 16 January 2009
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| Systematic name | YBL105C |
| Gene name | PKC1 |
| Aliases | CLY15, HPO2, STT1 |
| Feature type | ORF, Verified |
| Coordinates | Chr II:17696..14241 |
| Primary SGDID | S000000201 |
Description of YBL105C: Protein serine/threonine kinase essential for cell wall remodeling during growth; localized to sites of polarized growth and the mother-daughter bud neck; homolog of the alpha, beta, and gamma isoforms of mammalian protein kinase C (PKC)[1][2][3]
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Protein Details
Protein Modification
Modification(s): Phosphorylation
Identified as an efficient substrate of Clb2-Cdk1-as1 in a screen of a proteomic GST-fusion library. [4] [5]
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References
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- ↑ Watanabe M, et al. (1994) Saccharomyces cerevisiae PKC1 encodes a protein kinase C (PKC) homolog with a substrate specificity similar to that of mammalian PKC. J Biol Chem 269(24):16829-36 SGD PMID 8207005
- ↑ Andrews PD and Stark MJ (2000) Dynamic, Rho1p-dependent localization of Pkc1p to sites of polarized growth. J Cell Sci 113 ( Pt 15):2685-93 SGD PMID 10893184
- ↑ Levin DE, et al. (1994) Dissecting the protein kinase C/MAP kinase signalling pathway of Saccharomyces cerevisiae. Cell Mol Biol Res 40(3):229-39 SGD PMID 7874200
- ↑ Ubersax JA, et al. (2003) Targets of the cyclin-dependent kinase Cdk1. Nature 425(6960):859-64 SGD PMID 14574415
- ↑ submitted by Jeff Ubersax on 2004-01-21
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