Difference between revisions of "YBL088C"
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| + | Specifically higher expression in carbon limited chemostat cultures versus carbon excess. | ||
| + | <ref>Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur. | ||
| + | J Biol Chem 278(5):3265-74</ref> | ||
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Revision as of 13:02, 21 February 2007
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| Systematic name | YBL088C |
| Gene name | TEL1 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr II:59379..51016 |
Description of YBL088C: Protein kinase primarily involved in telomere length regulation; contributes to cell cycle checkpoint control in response to DNA damage; functionally redundant with Mec1p; homolog of human ataxia telangiectasia (ATM) gene[1][2][3][4]
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References
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- ↑ Nakada D, et al. (2003) The ATM-related Tel1 protein of Saccharomyces cerevisiae controls a checkpoint response following phleomycin treatment. Nucleic Acids Res 31(6):1715-24 SGD PMID 12626713
- ↑ Giannattasio M, et al. (2002) A dominant-negative MEC3 mutant uncovers new functions for the Rad17 complex and Tel1. Proc Natl Acad Sci U S A 99(20):12997-3002 SGD PMID 12271137
- ↑ Craven RJ, et al. (2002) Regulation of genome stability by TEL1 and MEC1, yeast homologs of the mammalian ATM and ATR genes. Genetics 161(2):493-507 SGD PMID 12072449
- ↑ Ritchie KB and Petes TD (2000) The Mre11p/Rad50p/Xrs2p complex and the Tel1p function in a single pathway for telomere maintenance in yeast. Genetics 155(1):475-9 SGD PMID 10790418
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