Difference between revisions of "YBL088C"

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'''Description of YBL088C:''' Protein kinase primarily involved in telomere length regulation; contributes to cell cycle checkpoint control in response to DNA damage; functionally redundant with Mec1p; homolog of human ataxia telangiectasia (ATM) gene<ref name='S000072773'>Nakada D, et al. (2003) The ATM-related Tel1 protein of Saccharomyces cerevisiae controls a checkpoint response following phleomycin treatment. Nucleic Acids Res 31(6):1715-24 {{SGDpaper|S000072773}} PMID 12626713</ref><ref name='S000071732'>Giannattasio M, et al. (2002) A dominant-negative MEC3 mutant uncovers new functions for the Rad17 complex and Tel1. Proc Natl Acad Sci U S A 99(20):12997-3002 {{SGDpaper|S000071732}} PMID 12271137</ref><ref name='S000070073'>Craven RJ, et al. (2002) Regulation of genome stability by TEL1 and MEC1, yeast homologs of the mammalian ATM and ATR genes. Genetics 161(2):493-507 {{SGDpaper|S000070073}} PMID 12072449</ref><ref name='S000040194'>Ritchie KB and Petes TD (2000) The Mre11p/Rad50p/Xrs2p complex and the Tel1p function in a single pathway for telomere maintenance in yeast. Genetics 155(1):475-9
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'''Description of YBL088C:''' Protein kinase primarily involved in telomere length regulation; contributes to cell cycle checkpoint control in response to DNA damage; functionally redundant with Mec1p; homolog of human ataxia telangiectasia (ATM) gene<ref name='S000040194'>Ritchie KB and Petes TD (2000) The Mre11p/Rad50p/Xrs2p complex and the Tel1p function in a single pathway for telomere maintenance in yeast. Genetics 155(1):475-9 {{SGDpaper|S000040194}} PMID 10790418</ref><ref name='S000070073'>Craven RJ, et al. (2002) Regulation of genome stability by TEL1 and MEC1, yeast homologs of the mammalian ATM and ATR genes. Genetics 161(2):493-507 {{SGDpaper|S000070073}} PMID 12072449</ref><ref name='S000071732'>Giannattasio M, et al. (2002) A dominant-negative MEC3 mutant uncovers new functions for the Rad17 complex and Tel1. Proc Natl Acad Sci U S A 99(20):12997-3002 {{SGDpaper|S000071732}} PMID 12271137</ref><ref name='S000072773'>Nakada D, et al. (2003) The ATM-related Tel1 protein of Saccharomyces cerevisiae controls a checkpoint response following phleomycin treatment. Nucleic Acids Res 31(6):1715-24
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  {{SGDpaper|S000072773}} PMID 12626713</ref>
 
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Revision as of 04:40, 18 December 2008

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Systematic name YBL088C
Gene name TEL1
Aliases
Feature type ORF, Verified
Coordinates Chr II:59379..51016
Primary SGDID S000000184


Description of YBL088C: Protein kinase primarily involved in telomere length regulation; contributes to cell cycle checkpoint control in response to DNA damage; functionally redundant with Mec1p; homolog of human ataxia telangiectasia (ATM) gene[1][2][3][4]




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References

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  1. Ritchie KB and Petes TD (2000) The Mre11p/Rad50p/Xrs2p complex and the Tel1p function in a single pathway for telomere maintenance in yeast. Genetics 155(1):475-9 SGD PMID 10790418
  2. Craven RJ, et al. (2002) Regulation of genome stability by TEL1 and MEC1, yeast homologs of the mammalian ATM and ATR genes. Genetics 161(2):493-507 SGD PMID 12072449
  3. Giannattasio M, et al. (2002) A dominant-negative MEC3 mutant uncovers new functions for the Rad17 complex and Tel1. Proc Natl Acad Sci U S A 99(20):12997-3002 SGD PMID 12271137
  4. Nakada D, et al. (2003) The ATM-related Tel1 protein of Saccharomyces cerevisiae controls a checkpoint response following phleomycin treatment. Nucleic Acids Res 31(6):1715-24 SGD PMID 12626713

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