Difference between revisions of "YBL046W"

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'''Description of YBL046W:''' Putative regulatory subunit of an evolutionarily conserved protein phosphatase complex containing the catalytic subunit Pph3p and a third subunit Psy2p; required for cisplatin resistance; homolog of mammalian R2<ref name='S000117297'>Hastie CJ, et al. (2006) The Saccharomyces cerevisiae orthologue of the human protein phosphatase 4 core regulatory subunit R2 confers resistance to the anticancer drug cisplatin. FEBS J 273(14):3322-34
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'''Description of YBL046W:''' Putative regulatory subunit of an evolutionarily conserved protein phosphatase; localization is cell-cycle dependant and regulated by Cdc28p phosphorylation; required for cisplatin resistance; homolog of mammalian R2<ref name='S000117297'>Hastie CJ, et al. (2006) The Saccharomyces cerevisiae orthologue of the human protein phosphatase 4 core regulatory subunit R2 confers resistance to the anticancer drug cisplatin. FEBS J 273(14):3322-34 {{SGDpaper|S000117297}} PMID 16857015</ref><ref name='S000130607'>Kosugi S, et al. (2009) Systematic identification of cell cycle-dependent yeast nucleocytoplasmic shuttling proteins by prediction of composite motifs. Proc Natl Acad Sci U S A
  {{SGDpaper|S000117297}} PMID 16857015</ref>
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  {{SGDpaper|S000130607}} PMID 19520826</ref>
 
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Revision as of 14:05, 22 June 2009

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Systematic name YBL046W
Gene name PSY4
Aliases
Feature type ORF, Verified
Coordinates Chr II:132427..133752
Primary SGDID S000000142


Description of YBL046W: Putative regulatory subunit of an evolutionarily conserved protein phosphatase; localization is cell-cycle dependant and regulated by Cdc28p phosphorylation; required for cisplatin resistance; homolog of mammalian R2[1][2]




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References

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  1. Hastie CJ, et al. (2006) The Saccharomyces cerevisiae orthologue of the human protein phosphatase 4 core regulatory subunit R2 confers resistance to the anticancer drug cisplatin. FEBS J 273(14):3322-34 SGD PMID 16857015
  2. Kosugi S, et al. (2009) Systematic identification of cell cycle-dependent yeast nucleocytoplasmic shuttling proteins by prediction of composite motifs. Proc Natl Acad Sci U S A SGD PMID 19520826

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