Difference between revisions of "YBL039C"

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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?dbid=S000000135 YBL039C]  
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000000135 YBL039C]  
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''URA7 ''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''URA7 ''
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
|nowrap| Chr II:145731..143992
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|nowrap| Chr II:145728..143989
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID'''          || S000000135
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID'''          || S000000135
 
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'''Description of YBL039C:''' Major CTP synthase isozyme (see also URA8), catalyzes the ATP-dependent transfer of the amide nitrogen from glutamine to UTP, forming CTP, the final step in de novo biosynthesis of pyrimidines; involved in phospholipid biosynthesis<ref name='S000065646'>McDonough VM, et al. (1995) Regulation of phospholipid biosynthesis in Saccharomyces cerevisiae by CTP. J Biol Chem 270(32):18774-80 {{SGDpaper|S000065646}} PMID 7642527</ref><ref name='S000051954'>Ozier-Kalogeropoulos O, et al. (1991) Cloning, sequencing and characterization of the Saccharomyces cerevisiae URA7 gene encoding CTP synthetase. Mol Gen Genet 231(1):7-16 {{SGDpaper|S000051954}} PMID 1753946</ref><ref name='S000049478'>Ostrander DB, et al. (1998) Effect of CTP synthetase regulation by CTP on phospholipid synthesis in Saccharomyces cerevisiae. J Biol Chem 273(30):18992-9001 {{SGDpaper|S000049478}} PMID 9668079</ref><ref name='S000046523'>Nadkarni AK, et al. (1995) Differential biochemical regulation of the URA7- and URA8-encoded CTP synthetases from Saccharomyces cerevisiae. J Biol Chem 270(42):24982-8 {{SGDpaper|S000046523}} PMID 7559626</ref><ref name='S000042459'>Ozier-Kalogeropoulos O, et al. (1994) Use of synthetic lethal mutants to clone and characterize a novel CTP synthetase gene in Saccharomyces cerevisiae. Mol Gen Genet 242(4):431-9 {{SGDpaper|S000042459}} PMID 8121398</ref><ref name='S000041184'>Yang WL, et al. (1994) Purification and characterization of CTP synthetase, the product of the URA7 gene in Saccharomyces cerevisiae. Biochemistry 33(35):10785-93
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'''Description of YBL039C:''' Major CTP synthase isozyme (see also URA8); catalyzes the ATP-dependent transfer of the amide nitrogen from glutamine to UTP, forming CTP, the final step in de novo biosynthesis of pyrimidines; involved in phospholipid biosynthesis; URA7 has a paralog, URA8, that arose from the whole genome duplication<ref name='S000113653'>Byrne KP and Wolfe KH (2005) The Yeast Gene Order Browser: combining curated homology and syntenic context reveals gene fate in polyploid species. Genome Res 15(10):1456-61 {{SGDpaper|S000113653}} PMID 16169922</ref><ref name='S000065646'>McDonough VM, et al. (1995) Regulation of phospholipid biosynthesis in Saccharomyces cerevisiae by CTP. J Biol Chem 270(32):18774-80 {{SGDpaper|S000065646}} PMID 7642527</ref><ref name='S000046523'>Nadkarni AK, et al. (1995) Differential biochemical regulation of the URA7- and URA8-encoded CTP synthetases from Saccharomyces cerevisiae. J Biol Chem 270(42):24982-8 {{SGDpaper|S000046523}} PMID 7559626</ref><ref name='S000049478'>Ostrander DB, et al. (1998) Effect of CTP synthetase regulation by CTP on phospholipid synthesis in Saccharomyces cerevisiae. J Biol Chem 273(30):18992-9001 {{SGDpaper|S000049478}} PMID 9668079</ref><ref name='S000051954'>Ozier-Kalogeropoulos O, et al. (1991) Cloning, sequencing and characterization of the Saccharomyces cerevisiae URA7 gene encoding CTP synthetase. Mol Gen Genet 231(1):7-16 {{SGDpaper|S000051954}} PMID 1753946</ref><ref name='S000042459'>Ozier-Kalogeropoulos O, et al. (1994) Use of synthetic lethal mutants to clone and characterize a novel CTP synthetase gene in Saccharomyces cerevisiae. Mol Gen Genet 242(4):431-9 {{SGDpaper|S000042459}} PMID 8121398</ref><ref name='S000041184'>Yang WL, et al. (1994) Purification and characterization of CTP synthetase, the product of the URA7 gene in Saccharomyces cerevisiae. Biochemistry 33(35):10785-93
 
  {{SGDpaper|S000041184}} PMID 8075080</ref>
 
  {{SGDpaper|S000041184}} PMID 8075080</ref>
 
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Latest revision as of 14:05, 31 August 2012

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Systematic name YBL039C
Gene name URA7
Aliases
Feature type ORF, Verified
Coordinates Chr II:145728..143989
Primary SGDID S000000135


Description of YBL039C: Major CTP synthase isozyme (see also URA8); catalyzes the ATP-dependent transfer of the amide nitrogen from glutamine to UTP, forming CTP, the final step in de novo biosynthesis of pyrimidines; involved in phospholipid biosynthesis; URA7 has a paralog, URA8, that arose from the whole genome duplication[1][2][3][4][5][6][7]




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References

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  1. Byrne KP and Wolfe KH (2005) The Yeast Gene Order Browser: combining curated homology and syntenic context reveals gene fate in polyploid species. Genome Res 15(10):1456-61 SGD PMID 16169922
  2. McDonough VM, et al. (1995) Regulation of phospholipid biosynthesis in Saccharomyces cerevisiae by CTP. J Biol Chem 270(32):18774-80 SGD PMID 7642527
  3. Nadkarni AK, et al. (1995) Differential biochemical regulation of the URA7- and URA8-encoded CTP synthetases from Saccharomyces cerevisiae. J Biol Chem 270(42):24982-8 SGD PMID 7559626
  4. Ostrander DB, et al. (1998) Effect of CTP synthetase regulation by CTP on phospholipid synthesis in Saccharomyces cerevisiae. J Biol Chem 273(30):18992-9001 SGD PMID 9668079
  5. Ozier-Kalogeropoulos O, et al. (1991) Cloning, sequencing and characterization of the Saccharomyces cerevisiae URA7 gene encoding CTP synthetase. Mol Gen Genet 231(1):7-16 SGD PMID 1753946
  6. Ozier-Kalogeropoulos O, et al. (1994) Use of synthetic lethal mutants to clone and characterize a novel CTP synthetase gene in Saccharomyces cerevisiae. Mol Gen Genet 242(4):431-9 SGD PMID 8121398
  7. Yang WL, et al. (1994) Purification and characterization of CTP synthetase, the product of the URA7 gene in Saccharomyces cerevisiae. Biochemistry 33(35):10785-93 SGD PMID 8075080

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