Difference between revisions of "YBL030C"

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'''Description of YBL030C:''' Major ADP/ATP carrier of the mitochondrial inner membrane, exchanges cytosolic ADP for mitochondrially synthesized ATP; phosphorylated; required for viability in many common lab strains carrying a mutation in the polymorphic SAL1 gene<ref name='S000056982'>Adrian GS, et al. (1986) Sequences required for delivery and localization of the ADP/ATP translocator to the mitochondrial inner membrane. Mol Cell Biol 6(2):626-34 {{SGDpaper|S000056982}} PMID 3023860</ref><ref name='S000076579'>Chen XJ (2004) Sal1p, a calcium-dependent carrier protein that suppresses an essential cellular function associated With the Aac2 isoform of ADP/ATP translocase in Saccharomyces cerevisiae. Genetics 167(2):607-17 {{SGDpaper|S000076579}} PMID 15238515</ref><ref name='S000123951'>Reinders J, et al. (2007) Profiling phosphoproteins of yeast mitochondria reveals a role of phosphorylation in assembly of the ATP synthase. Mol Cell Proteomics 6(11):1896-906
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'''Description of YBL030C:''' Major ADP/ATP carrier of the mitochondrial inner membrane, exchanges cytosolic ADP for mitochondrially synthesized ATP; also imports heme and ATP; phosphorylated; required for viability in many lab strains that carry a sal1 mutation<ref name='S000056982'>Adrian GS, et al. (1986) Sequences required for delivery and localization of the ADP/ATP translocator to the mitochondrial inner membrane. Mol Cell Biol 6(2):626-34 {{SGDpaper|S000056982}} PMID 3023860</ref><ref name='S000127569'>Azuma M, et al. (2008) Adenine nucleotide translocator transports haem precursors into mitochondria. PLoS ONE 3(8):e3070 {{SGDpaper|S000127569}} PMID 18728780</ref><ref name='S000076579'>Chen XJ (2004) Sal1p, a calcium-dependent carrier protein that suppresses an essential cellular function associated With the Aac2 isoform of ADP/ATP translocase in Saccharomyces cerevisiae. Genetics 167(2):607-17 {{SGDpaper|S000076579}} PMID 15238515</ref><ref name='S000123951'>Reinders J, et al. (2007) Profiling phosphoproteins of yeast mitochondria reveals a role of phosphorylation in assembly of the ATP synthase. Mol Cell Proteomics 6(11):1896-906 {{SGDpaper|S000123951}} PMID 17761666</ref><ref name='S000126530'>Traba J, et al. (2008) Yeast mitochondria import ATP through the calcium-dependent ATP-Mg/Pi carrier Sal1p, and are ATP consumers during aerobic growth in glucose. Mol Microbiol 69(3):570-85
  {{SGDpaper|S000123951}} PMID 17761666</ref>
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  {{SGDpaper|S000126530}} PMID 18485069</ref>
 
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Revision as of 14:05, 8 March 2010

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Systematic name YBL030C
Gene name PET9
Aliases AAC2, ANC2, OP1
Feature type ORF, Verified
Coordinates Chr II:164000..163044
Primary SGDID S000000126


Description of YBL030C: Major ADP/ATP carrier of the mitochondrial inner membrane, exchanges cytosolic ADP for mitochondrially synthesized ATP; also imports heme and ATP; phosphorylated; required for viability in many lab strains that carry a sal1 mutation[1][2][3][4][5]




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References

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  1. Adrian GS, et al. (1986) Sequences required for delivery and localization of the ADP/ATP translocator to the mitochondrial inner membrane. Mol Cell Biol 6(2):626-34 SGD PMID 3023860
  2. Azuma M, et al. (2008) Adenine nucleotide translocator transports haem precursors into mitochondria. PLoS ONE 3(8):e3070 SGD PMID 18728780
  3. Chen XJ (2004) Sal1p, a calcium-dependent carrier protein that suppresses an essential cellular function associated With the Aac2 isoform of ADP/ATP translocase in Saccharomyces cerevisiae. Genetics 167(2):607-17 SGD PMID 15238515
  4. Reinders J, et al. (2007) Profiling phosphoproteins of yeast mitochondria reveals a role of phosphorylation in assembly of the ATP synthase. Mol Cell Proteomics 6(11):1896-906 SGD PMID 17761666
  5. Traba J, et al. (2008) Yeast mitochondria import ATP through the calcium-dependent ATP-Mg/Pi carrier Sal1p, and are ATP consumers during aerobic growth in glucose. Mol Microbiol 69(3):570-85 SGD PMID 18485069

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