Difference between revisions of "YBL020W"

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==Community Commentary==
 
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==References==
 
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Revision as of 08:17, 30 January 2007

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Systematic name YBL020W
Gene name RFT1
Aliases
Feature type ORF, Verified
Coordinates Chr II:182404..184128


Description of YBL020W: Flippase, essential integral membrane protein that is required for translocation of Man5GlcNac2-PP-Dol from the cytoplasmic side to the lumenal side of the ER membrane; mutation is suppressed by expression human p53 protein[1][2]




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Community Commentary

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References

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  1. Helenius J, et al. (2002) Translocation of lipid-linked oligosaccharides across the ER membrane requires Rft1 protein. Nature 415(6870):447-50 SGD PMID 11807558
  2. Koerte A, et al. (1995) Suppression of the yeast mutation rft1-1 by human p53. J Biol Chem 270(38):22556-64 SGD PMID 7673248

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