Difference between revisions of "YBL008W"
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| − | '''Description of YBL008W:''' Subunit of the HIR complex, a nucleosome assembly complex involved in regulation of histone gene transcription; contributes to nucleosome formation, heterochromatic gene silencing, and formation of functional kinetochores<ref name=' | + | '''Description of YBL008W:''' Subunit of the HIR complex, a nucleosome assembly complex involved in regulation of histone gene transcription; contributes to nucleosome formation, heterochromatic gene silencing, and formation of functional kinetochores<ref name='S000087068'>Prochasson P, et al. (2005) The HIR corepressor complex binds to nucleosomes generating a distinct protein/DNA complex resistant to remodeling by SWI/SNF. Genes Dev 19(21):2534-9 {{SGDpaper|S000087068}} PMID 16264190</ref><ref name='S000069112'>Sharp JA, et al. (2002) Chromatin assembly factor I and Hir proteins contribute to building functional kinetochores in S. cerevisiae. Genes Dev 16(1):85-100 {{SGDpaper|S000069112}} PMID 11782447</ref><ref name='S000065877'>Sharp JA, et al. (2001) Yeast histone deposition protein Asf1p requires Hir proteins and PCNA for heterochromatic silencing. Curr Biol 11(7):463-73 {{SGDpaper|S000065877}} PMID 11412995</ref><ref name='S000055143'>Spector MS, et al. (1997) Hir1p and Hir2p function as transcriptional corepressors to regulate histone gene transcription in the Saccharomyces cerevisiae cell cycle. Mol Cell Biol 17(2):545-52 {{SGDpaper|S000055143}} PMID 9001207</ref><ref name='S000048249'>Sherwood PW, et al. (1993) Characterization of HIR1 and HIR2, two genes required for regulation of histone gene transcription in Saccharomyces cerevisiae. Mol Cell Biol 13(1):28-38 {{SGDpaper|S000048249}} PMID 8417331</ref><ref name='S000043368'>Kaufman PD, et al. (1998) Hir proteins are required for position-dependent gene silencing in Saccharomyces cerevisiae in the absence of chromatin assembly factor I. Mol Cell Biol 18(8):4793-806 {{SGDpaper|S000043368}} PMID 9671489</ref><ref name='S000039248'>DeSilva H, et al. (1998) Functional dissection of yeast Hir1p, a WD repeat-containing transcriptional corepressor. Genetics 148(2):657-67 |
| − | {{SGDpaper| | + | {{SGDpaper|S000039248}} PMID 9504914</ref> |
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Revision as of 14:05, 16 January 2009
Share your knowledge...Edit this entry! <protect>
| Systematic name | YBL008W |
| Gene name | HIR1 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr II:209656..212178 |
| Primary SGDID | S000000104 |
Description of YBL008W: Subunit of the HIR complex, a nucleosome assembly complex involved in regulation of histone gene transcription; contributes to nucleosome formation, heterochromatic gene silencing, and formation of functional kinetochores[1][2][3][4][5][6][7]
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References
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- ↑ Prochasson P, et al. (2005) The HIR corepressor complex binds to nucleosomes generating a distinct protein/DNA complex resistant to remodeling by SWI/SNF. Genes Dev 19(21):2534-9 SGD PMID 16264190
- ↑ Sharp JA, et al. (2002) Chromatin assembly factor I and Hir proteins contribute to building functional kinetochores in S. cerevisiae. Genes Dev 16(1):85-100 SGD PMID 11782447
- ↑ Sharp JA, et al. (2001) Yeast histone deposition protein Asf1p requires Hir proteins and PCNA for heterochromatic silencing. Curr Biol 11(7):463-73 SGD PMID 11412995
- ↑ Spector MS, et al. (1997) Hir1p and Hir2p function as transcriptional corepressors to regulate histone gene transcription in the Saccharomyces cerevisiae cell cycle. Mol Cell Biol 17(2):545-52 SGD PMID 9001207
- ↑ Sherwood PW, et al. (1993) Characterization of HIR1 and HIR2, two genes required for regulation of histone gene transcription in Saccharomyces cerevisiae. Mol Cell Biol 13(1):28-38 SGD PMID 8417331
- ↑ Kaufman PD, et al. (1998) Hir proteins are required for position-dependent gene silencing in Saccharomyces cerevisiae in the absence of chromatin assembly factor I. Mol Cell Biol 18(8):4793-806 SGD PMID 9671489
- ↑ DeSilva H, et al. (1998) Functional dissection of yeast Hir1p, a WD repeat-containing transcriptional corepressor. Genetics 148(2):657-67 SGD PMID 9504914
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