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Systematic name YBL003C
Gene name HTA2
Aliases H2A2
Feature type ORF, Verified
Coordinates Chr II:235792..235394
Primary SGDID S000000099

Description of YBL003C: Histone H2A, core histone protein required for chromatin assembly and chromosome function; one of two nearly identical (see also HTA1) subtypes; DNA damage-dependent phosphorylation by Mec1p facilitates DNA repair; acetylated by Nat4p[1][2][3][4][5]


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  1. Choe J, et al. (1982) The two yeast histone H2A genes encode similar protein subtypes. Proc Natl Acad Sci U S A 79(5):1484-7 SGD PMID 7041122
  2. Downs JA, et al. (2000) A role for Saccharomyces cerevisiae histone H2A in DNA repair. Nature 408(6815):1001-4 SGD PMID 11140636
  3. Meeks-Wagner D and Hartwell LH (1986) Normal stoichiometry of histone dimer sets is necessary for high fidelity of mitotic chromosome transmission. Cell 44(1):43-52 SGD PMID 3510079
  4. Norris D, et al. (1988) The effect of histone gene deletions on chromatin structure in Saccharomyces cerevisiae. Science 242(4879):759-61 SGD PMID 2847314
  5. Song OK, et al. (2003) An Nalpha-acetyltransferase responsible for acetylation of the N-terminal residues of histones H4 and H2A. J Biol Chem 278(40):38109-12 SGD PMID 12915400

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