YAL062W

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Systematic name YAL062W
Gene name GDH3
Aliases FUN51
Feature type ORF, Verified
Coordinates Chr I:31567..32940
Primary SGDID S000000058


Description of YAL062W: NADP(+)-dependent glutamate dehydrogenase, synthesizes glutamate from ammonia and alpha-ketoglutarate; rate of alpha-ketoglutarate utilization differs from Gdh1p; expression regulated by nitrogen and carbon sources[1][2][3]




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References

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  1. Avendano A, et al. (1997) GDH3 encodes a glutamate dehydrogenase isozyme, a previously unrecognized route for glutamate biosynthesis in Saccharomyces cerevisiae. J Bacteriol 179(17):5594-7 SGD PMID 9287019
  2. DeLuna A, et al. (2001) NADP-glutamate dehydrogenase isoenzymes of Saccharomyces cerevisiae. Purification, kinetic properties, and physiological roles. J Biol Chem 276(47):43775-83 SGD PMID 11562373
  3. Riego L, et al. (2002) GDH1 expression is regulated by GLN3, GCN4, and HAP4 under respiratory growth. Biochem Biophys Res Commun 293(1):79-85 SGD PMID 12054566

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