Difference between revisions of "YAL056W"
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| − | '''Description of YAL056W:''' | + | '''Description of YAL056W:''' Regulator of cAMP-PKA signaling that functions downstream of Gpa2p and Cyr1p to directly inhibit protein kinase A, increasing its cAMP dependancy; regulated directly by the G-alpha protein Gpa2p; kelch-repeat containing Gpb1p homolog<ref name='S000123081'>Niranjan T, et al. (2007) Kelch Repeat Protein Interacts with the Yeast G{alpha} Subunit Gpa2p at a Site That Couples Receptor Binding to Guanine Nucleotide Exchange. J Biol Chem 282(33):24231-8 {{SGDpaper|S000123081}} PMID 17584745</ref><ref name='S000118053'>Peeters T, et al. (2006) Kelch-repeat proteins interacting with the Galpha protein Gpa2 bypass adenylate cyclase for direct regulation of protein kinase A in yeast. Proc Natl Acad Sci U S A 103(35):13034-9 {{SGDpaper|S000118053}} PMID 16924114</ref><ref name='S000087180'>Lu A and Hirsch JP (2005) Cyclic AMP-independent regulation of protein kinase A substrate phosphorylation by Kelch repeat proteins. Eukaryot Cell 4(11):1794-800 {{SGDpaper|S000087180}} PMID 16278446</ref><ref name='S000073959'>Batlle M, et al. (2003) Krh1p and Krh2p act downstream of the Gpa2p G(alpha) subunit to negatively regulate haploid invasive growth. J Cell Sci 116(Pt 4):701-10 {{SGDpaper|S000073959}} PMID 12538771</ref><ref name='S000070204'>Harashima T and Heitman J (2002) The Galpha protein Gpa2 controls yeast differentiation by interacting with kelch repeat proteins that mimic Gbeta subunits. Mol Cell 10(1):163-73 |
{{SGDpaper|S000070204}} PMID 12150916</ref> | {{SGDpaper|S000070204}} PMID 12150916</ref> | ||
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Revision as of 14:05, 4 December 2007
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| Systematic name | YAL056W |
| Gene name | GPB2 |
| Aliases | KRH1 |
| Feature type | ORF, Verified |
| Coordinates | Chr I:39260..41902 |
| Primary SGDID | S000000052 |
Description of YAL056W: Regulator of cAMP-PKA signaling that functions downstream of Gpa2p and Cyr1p to directly inhibit protein kinase A, increasing its cAMP dependancy; regulated directly by the G-alpha protein Gpa2p; kelch-repeat containing Gpb1p homolog[1][2][3][4][5]
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Contents
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References
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- ↑ Niranjan T, et al. (2007) Kelch Repeat Protein Interacts with the Yeast G{alpha} Subunit Gpa2p at a Site That Couples Receptor Binding to Guanine Nucleotide Exchange. J Biol Chem 282(33):24231-8 SGD PMID 17584745
- ↑ Peeters T, et al. (2006) Kelch-repeat proteins interacting with the Galpha protein Gpa2 bypass adenylate cyclase for direct regulation of protein kinase A in yeast. Proc Natl Acad Sci U S A 103(35):13034-9 SGD PMID 16924114
- ↑ Lu A and Hirsch JP (2005) Cyclic AMP-independent regulation of protein kinase A substrate phosphorylation by Kelch repeat proteins. Eukaryot Cell 4(11):1794-800 SGD PMID 16278446
- ↑ Batlle M, et al. (2003) Krh1p and Krh2p act downstream of the Gpa2p G(alpha) subunit to negatively regulate haploid invasive growth. J Cell Sci 116(Pt 4):701-10 SGD PMID 12538771
- ↑ Harashima T and Heitman J (2002) The Galpha protein Gpa2 controls yeast differentiation by interacting with kelch repeat proteins that mimic Gbeta subunits. Mol Cell 10(1):163-73 SGD PMID 12150916
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