Difference between revisions of "YAL043C"
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| − | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http:// | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000000041 YAL043C] |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''PTA1 '' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''PTA1 '' | ||
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | ||
| − | |nowrap| Chr I: | + | |nowrap| Chr I:61052..58695 |
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| + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID''' || S000000041 | ||
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| − | '''Description of | + | '''Description of YAL043C:''' Subunit of holo-CPF, a multiprotein complex and functional homolog of mammalian CPSF, required for the cleavage and polyadenylation of mRNA and snoRNA 3' ends; involved in pre-tRNA processing; binds to the phosphorylated CTD of RNAPII<ref name='S000074089'>Nedea E, et al. (2003) Organization and function of APT, a subcomplex of the yeast cleavage and polyadenylation factor involved in the formation of mRNA and small nucleolar RNA 3'-ends. J Biol Chem 278(35):33000-10 {{SGDpaper|S000074089}} PMID 12819204</ref><ref name='S000045390'>O'Connor JP and Peebles CL (1992) PTA1, an essential gene of Saccharomyces cerevisiae affecting pre-tRNA processing. Mol Cell Biol 12(9):3843-56 {{SGDpaper|S000045390}} PMID 1508188</ref><ref name='S000040911'>Preker PJ, et al. (1997) A multisubunit 3' end processing factor from yeast containing poly(A) polymerase and homologues of the subunits of mammalian cleavage and polyadenylation specificity factor. EMBO J 16(15):4727-37 {{SGDpaper|S000040911}} PMID 9303317</ref><ref name='S000050929'>Rodriguez CR, et al. (2000) Kin28, the TFIIH-associated carboxy-terminal domain kinase, facilitates the recruitment of mRNA processing machinery to RNA polymerase II. Mol Cell Biol 20(1):104-12 {{SGDpaper|S000050929}} PMID 10594013</ref><ref name='S000046866'>Zhao J, et al. (1999) Pta1, a component of yeast CF II, is required for both cleavage and poly(A) addition of mRNA precursor. Mol Cell Biol 19(11):7733-40 |
| − | {{SGDpaper| | + | {{SGDpaper|S000046866}} PMID 10523662</ref> |
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J Biol Chem 278(5):3265-74</ref> | J Biol Chem 278(5):3265-74</ref> | ||
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Latest revision as of 07:45, 23 January 2012
Share your knowledge...Edit this entry! <protect>
| Systematic name | YAL043C |
| Gene name | PTA1 |
| Aliases | FUN39 |
| Feature type | ORF, Verified |
| Coordinates | Chr I:61052..58695 |
| Primary SGDID | S000000041 |
Description of YAL043C: Subunit of holo-CPF, a multiprotein complex and functional homolog of mammalian CPSF, required for the cleavage and polyadenylation of mRNA and snoRNA 3' ends; involved in pre-tRNA processing; binds to the phosphorylated CTD of RNAPII[1][2][3][4][5]
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References
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- ↑ Nedea E, et al. (2003) Organization and function of APT, a subcomplex of the yeast cleavage and polyadenylation factor involved in the formation of mRNA and small nucleolar RNA 3'-ends. J Biol Chem 278(35):33000-10 SGD PMID 12819204
- ↑ O'Connor JP and Peebles CL (1992) PTA1, an essential gene of Saccharomyces cerevisiae affecting pre-tRNA processing. Mol Cell Biol 12(9):3843-56 SGD PMID 1508188
- ↑ Preker PJ, et al. (1997) A multisubunit 3' end processing factor from yeast containing poly(A) polymerase and homologues of the subunits of mammalian cleavage and polyadenylation specificity factor. EMBO J 16(15):4727-37 SGD PMID 9303317
- ↑ Rodriguez CR, et al. (2000) Kin28, the TFIIH-associated carboxy-terminal domain kinase, facilitates the recruitment of mRNA processing machinery to RNA polymerase II. Mol Cell Biol 20(1):104-12 SGD PMID 10594013
- ↑ Zhao J, et al. (1999) Pta1, a component of yeast CF II, is required for both cleavage and poly(A) addition of mRNA precursor. Mol Cell Biol 19(11):7733-40 SGD PMID 10523662
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