YAL040C
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| Systematic name | YAL040C | |
| Gene name | CLN3 | |
| Aliases | DAF1, FUN10, WHI1 | |
| Feature type | ORF, Verified | |
| Coordinates | Chr I:67521..65779 | |
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Description of YAL040C: G1 cyclin involved in cell cycle progression; activates Cdc28p kinase to promote the G1 to S phase transition; plays a role in regulating transcription of the other G1 cyclins, CLN1 and CLN2; regulated by phosphorylation and proteolysis[1][2][3]
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References
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- ↑ Tyers M, et al. (1992) The Cln3-Cdc28 kinase complex of S. cerevisiae is regulated by proteolysis and phosphorylation. EMBO J 11(5):1773-84 SGD PMID 1316273
- ↑ Nash R, et al. (1988) The WHI1+ gene of Saccharomyces cerevisiae tethers cell division to cell size and is a cyclin homolog. EMBO J 7(13):4335-46 SGD PMID 2907481
- ↑ Cross FR and Blake CM (1993) The yeast Cln3 protein is an unstable activator of Cdc28. Mol Cell Biol 13(6):3266-71 SGD PMID 8497251
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