YAL035W

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Systematic name YAL035W
Gene name FUN12
Aliases yIF2
Feature type ORF, Verified
Coordinates Chr I:76428..79436
Primary SGDID S000000033


Description of YAL035W: GTPase, required for general translation initiation by promoting Met-tRNAiMet binding to ribosomes and ribosomal subunit joining; homolog of bacterial IF2[1][2]




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References

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  1. Choi SK, et al. (1998) Promotion of met-tRNAiMet binding to ribosomes by yIF2, a bacterial IF2 homolog in yeast. Science 280(5370):1757-60 SGD PMID 9624054
  2. Lee JH, et al. (2002) Initiation factor eIF5B catalyzes second GTP-dependent step in eukaryotic translation initiation. Proc Natl Acad Sci U S A 99(26):16689-94 SGD PMID 12471154

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